Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 10/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632490 | 0.86 | MAPT (0.43) | CYP2D6DYRK1A | |
| SCHEMBL17632611 | 0.85 | RAB9A (0.37) | CYP2D6DYRK1APPARA | |
| SCHEMBL17631984 | 0.84 | DYRK1A (0.33) | DYRK1A | |
| SCHEMBL17632621 | 0.83 | ALDH1A1 (0.47) | USP30 | |
| SCHEMBL17632007 | 0.82 | LIPG (0.41) | — | |
| SCHEMBL17632020 | 0.82 | MAPT (0.46) | DYRK1AUSP30 | |
| SCHEMBL17631550 | 0.79 | ABL1 (0.41) | — | |
| SCHEMBL17632035 | 0.79 | ABL1 (0.45) | — | |
| SCHEMBL17632415 | 0.78 | CHEK1 (0.41) | DYRK1ASLC6A4USP30 | |
| SCHEMBL17632567 | 0.77 | BRD4 (0.47) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |