Sugi Predict

Sugi Predict / Compounds / SCHEMBL1765069

SCHEMBL1765069

SCHEMBL1765069

O=C(OC1CCCc2ccccc21)c1csc(C2CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 3/20 0.34
▸ GAA P10253 4/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ PPARG P37231 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ CTSV O60911 1/20 0.30
▸ CTSL P07711 1/20 0.30
▸ CTSS P25774 1/20 0.30
▸ CTSK P43235 1/20 0.30
▸ FFAR1 O14842 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ AADAT Q8N5Z0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765067 1.00 FAAH (0.34) FAAHGAAALDH1A1KMT2ASMN1; SMN2
SCHEMBL29814837 1.00 FAAH (0.34) FAAHGAAALDH1A1KMT2ASMN1; SMN2
SCHEMBL1765540 1.00 FAAH (0.34) FAAHGAAALDH1A1KMT2ASMN1; SMN2
SCHEMBL1120023 0.84 ALDH1A1 (0.34) FAAHGAAALDH1A1KMT2ASMN1; SMN2
SCHEMBL1765621 0.83 GAA (0.41) GAAALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL1765072 0.83 GAA (0.41) GAAALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL1765070 0.83 GAA (0.41) GAAALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL440115 0.82 HRH3 (0.35) GAAALDH1A1KMT2AMEN1LMNA
SCHEMBL15446675 0.82 ALDH1A1 (0.43) GAAALDH1A1KMT2APPARGHPGD
SCHEMBL1119900 0.81 ALDH1A1 (0.36) FAAHGAAALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150266850-A1 SUBSTITUTED TOLYL FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2015-09-24 — — US claimed
US-20110124501-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-26 — — US claimed
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 — — US disclosed
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles FMC CORPORATION (US) 2025-08-26 — — US disclosed
US-20240324596-A1 SUBSTITUTED TOLYL FUNGICIDES FMC CORPORATION 2024-10-03 — — US disclosed
EP-4388876-A2 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC Corporation (US) 2024-06-26 — — EP disclosed
US-20240166638-A1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2024-05-23 — — US disclosed
EP-3847160-B1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORP (US) 2024-05-08 — — EP disclosed
EP-3558984-B1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2023-08-02 — — EP disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 — — US disclosed
US-20230131966-A1 FUNGICIDAL AMIDES FMC CORPORATION 2023-04-27 — — US disclosed
US-9464056-B2 Fungicidal 4-methylanilino pyrazoles E I DU PONT DE NEMOURS AND COMPANY (US) 2016-10-11 — — US disclosed
WO-2016149311-A1 FUNGICIDAL PYRAZOLES E I DU PONT DE NEMOURS AND COMPANY (US) 2016-09-22 — — WO disclosed
US-20160242416-A1 FUNGICIDAL ISOXAZOLINE CARBINOLS DU PONT (US) 2016-08-25 — — US disclosed
EP-2864293-B1 FUNGICIDAL 4-METHYLANILINO PYRAZOLES DU PONT (US) 2016-04-27 — — EP disclosed
US-20160081337-A1 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-03-24 — — US disclosed
US-20160050925-A1 FUNGICIDAL AMIDES FMC CORPORATION 2016-02-25 — — US disclosed
US-20150307456-A1 FUNGICIDAL 4-METHYLANILINO PYRAZOLES FMC CORPORATION 2015-10-29 — — US disclosed
US-20150266850-A1 SUBSTITUTED TOLYL FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2015-09-24 — — US disclosed
US-20110124501-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160081337-A1 FUNGICIDAL AMIDES CYP1B1, CYP1A1, CBR1 FAAH 2116/4885GAA 322/4885ALDH1A1 127/4885
US-20110124501-A1 Active compound combinations CYP51A1, CA4, BROX FAAH 2218/4885GAA 90/4885ALDH1A1 240/4885
US-20150266850-A1 SUBSTITUTED TOLYL FUNGICIDES TH, CYP1B1, CYP1A1 FAAH 3612/4885GAA 369/4885ALDH1A1 544/4885
US-20240166638-A1 FUNGICIDAL OXADIAZOLES OXA1L, NOX1, TH FAAH 4329/4885GAA 516/4885ALDH1A1 603/4885
US-20160050925-A1 FUNGICIDAL AMIDES CBR1, CBR3, PRXL2A FAAH 2239/4885GAA 714/4885ALDH1A1 945/4885
US-20240324596-A1 SUBSTITUTED TOLYL FUNGICIDES TH, NAT1, CYP1B1 FAAH 4132/4885GAA 500/4885ALDH1A1 1104/4885
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles TH, NOX1, NOX3 FAAH 4172/4885GAA 1484/4885ALDH1A1 1766/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 FAAH 2018/4885GAA 2552/4885ALDH1A1 2861/4885
US-20230131966-A1 FUNGICIDAL AMIDES ARG1, CYP1B1, NOX1 FAAH 2102/4885GAA 527/4885ALDH1A1 1093/4885
US-20160242416-A1 FUNGICIDAL ISOXAZOLINE CARBINOLS CYP1B1, CHRM1, CYP1A1 FAAH 4100/4885GAA 1896/4885ALDH1A1 499/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH FAAH 4329/4885GAA 516/4885ALDH1A1 603/4885
US-20150307456-A1 FUNGICIDAL 4-METHYLANILINO PYRAZOLES CYP2F1, CYP1B1, CYP4B1 FAAH 3407/4885GAA 3635/4885ALDH1A1 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.