Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.37 | |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 4/20 | 0.34 |
| ▸ | NMT1 | P30419 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661798 | 0.86 | FURIN (0.42) | FURINPDFITGB1ITGA4KLKB1 | |
| SCHEMBL16645085 | 0.82 | FURIN (0.45) | FURINPDFKLKB1SMN1; SMN2NMT2 | |
| SCHEMBL16274147 | 0.82 | FAP (0.38) | FURINPDFKLKB1NMT2NMT1 | |
| SCHEMBL15686242 | 0.80 | NMT2 (0.45) | FURINPDFKLKB1NMT2NMT1 | |
| SCHEMBL17860166 | 0.80 | FURIN (0.38) | FURINPDFKLKB1SMN1; SMN2HTT | |
| SCHEMBL19776894 | 0.80 | FURIN (0.38) | FURINPDFKLKB1SMN1; SMN2HTT | |
| SCHEMBL26423089 | 0.79 | NMT2 (0.40) | FURINPDFKLKB1NMT2NMT1 | |
| Bicarbonate SCHEMBL30831304 | 0.78 | PDF (0.41) | FURINPDFITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL24864487 | 0.76 | KLKB1 (0.44) | FURINPDFITGB1KLKB1NMT2 | |
| SCHEMBL20332469 | 0.76 | CA2 (0.45) | FURINHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | SHBG, PTMS, VIP | FURIN 78/4885PDF 238/4885ITGB1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.