Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.43 |
| ▸ | ALPL | P05186 | 5/20 | 0.43 |
| ▸ | XIAP | P98170 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946984 | 0.77 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL28981274 | 0.77 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL19479233 | 0.77 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17675171 | 0.77 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4436614 | 0.75 | TSHR (0.47) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL29087084 | 0.75 | TSHR (0.47) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL5329831 | 0.72 | TSHR (0.58) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4436617 | 0.72 | TSHR (0.44) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL22622062 | 0.71 | TSHR (0.52) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1862337 | 0.71 | TSHR (0.62) | TSHRALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624196-B2 | Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition | DENKA COMPANY LIMITED (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12492279-B2 | Chloroprene-based block copolymer, latex, latex composition, and rubber composition | DENKA COMPANY LIMITED (JP) | 2025-12-09 | — | — | US | disclosed |
| EP-4282889-B1 | (METH)ACRYLIC BLOCK COPOLYMER, (METH)ACRYLIC BLOCK COPOLYMER LATEX, (METH)ACRYLIC BLOCK COPOLYMER LATEX COMPOSITION, AND SHAPED OBJECT | DENKA COMPANY LTD (JP) | 2025-08-20 | — | — | EP | disclosed |
| US-12312433-B2 | Chloroprene-based block copolymer, latex, latex composition, and rubber composition | DENKA COMPANY LIMITED (JP) | 2025-05-27 | — | — | US | disclosed |
| WO-2025053025-A1 | BLOCK COPOLYMER | デンカ株式会社 | 2025-03-13 | — | — | WO | disclosed |
| EP-4223837-B1 | RUBBER COMPOSITION, VULCANIZED PRODUCT, AND VULCANIZED MOLDED ARTICLE | DENKA COMPANY LTD (JP) | 2024-12-25 | — | — | EP | disclosed |
| EP-4144814-B1 | RUBBER REINFORCING MATERIAL AND METHOD FOR PRODUCING SAME, AND RUBBER ARTICLE | DENKA COMPANY LTD (JP) | 2024-11-20 | — | — | EP | disclosed |
| EP-4227353-B1 | RUBBER COMPOSITION, VULCANIZED SUBSTANCE, AND VULCANIZED MOLDED OBJECT | DENKA COMPANY LTD (JP) | 2024-11-06 | — | — | EP | disclosed |
| US-20240352175-A1 | CHLOROPRENE BLOCK COPOLYMER, LATEX, LATEX COMPOSITION, AND RUBBER COMPOSITION | DENKA COMPANY LIMITED (JP) | 2024-10-24 | — | — | US | disclosed |
| EP-4253466-B1 | RUBBER COMPOSITION, VULCANIZED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION, AND VULCANIZED MOLDED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION | DENKA COMPANY LTD (JP) | 2024-10-02 | — | — | EP | disclosed |
| EP-3660057-A1 | POLYMER MANUFACTURING METHOD | Denka Company Limited (JP) | 2020-06-03 | — | — | EP | disclosed |
| US-20200165421-A1 | CHLOROPRENE POLYMER AND PRODUCTION METHOD THEREFOR | DENKA COMPANY LIMITED (JP) | 2020-05-28 | — | — | US | disclosed |
| EP-3656795-A1 | CHLOROPRENE POLYMER AND PRODUCTION METHOD THEREFOR | Denka Company Limited (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3636675-A1 | METHOD FOR PRODUCING STATISTICAL COPOLYMER CONTAINING CHLOROPRENE MONOMER UNIT AND UNSATURATED NITRILE MONOMER UNIT, STATISTICAL COPOLYMER, LATEX AND USE OF SAME | Denka Company Limited (JP) | 2020-04-15 | — | — | EP | disclosed |
| WO-2020044899-A1 | COPOLYMER OF CHLOROPRENE MONOMER AND UNSATURATED NITRILE COMPOUND, COMPOSITION CONTAINING COPOLYMER, VULCANIZATION MOLDED BODY OF COMPOSITION, AND USE OF VULCANIZATION MOLDED BODY | デンカ株式会社 | 2020-03-05 | — | — | WO | disclosed |
| EP-3604367-A1 | BLOCK COPOLYMER AND METHOD FOR PRODUCING BLOCK COPOLYMER | Denka Company Limited (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20170298026-A1 | ALL PURPOSE RAFT AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2017-10-19 | — | — | US | disclosed |
| EP-3204353-A1 | ALL PURPOSE RAFT AGENT | Commonwealth Scientific and Industrial Research Organisation (AU) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016055858-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | ASTRAZENECA AB (SE) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016054689-A1 | ALL PURPOSE RAFT AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298026-A1 | ALL PURPOSE RAFT AGENT | NPC1L1, RFTN1, SGMS2 | TSHR 4058/4885ALDH1A1 817/4885MEN1 1909/4885 |
| US-12624196-B2 | Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition | ALG3, VCL, DNMT1 | TSHR 4144/4885ALDH1A1 2251/4885MEN1 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.