Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768591 | 1.00 | CYP26A1 (0.43) | CYP26A1KDM4ECYP17A1SLC7A5TBXAS1 | |
| SCHEMBL1768589 | 1.00 | CYP26A1 (0.43) | CYP26A1KDM4ECYP17A1SLC7A5TBXAS1 | |
| SCHEMBL27968394 | 0.81 | CYP26A1 (0.45) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| Valine SCHEMBL11057433 | 0.81 | SLC7A5 (0.48) | CYP26A1KDM4ECYP17A1SLC7A5TBXAS1 | |
| SCHEMBL20518637 | 0.77 | KDM4E (0.45) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| SCHEMBL2585276 | 0.77 | KDM4E (0.45) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| Hydrochloric Acid SCHEMBL28339290 | 0.76 | TBXAS1 (0.40) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| Bromide SCHEMBL28354965 | 0.76 | KDM4E (0.44) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| Hydrochloric Acid SCHEMBL27966647 | 0.76 | KDM4E (0.44) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 | |
| Bicarbonate SCHEMBL28505567 | 0.75 | KDM4E (0.46) | CYP26A1KDM4ECYP17A1TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| EP-3280723-B1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-01-06 | — | — | EP | disclosed |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2020-11-10 | — | — | US | disclosed |
| EP-3707153-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2020-09-16 | — | — | EP | disclosed |
| US-10730911-B2 | Backbone-cyclized peptidomimetics with GLP-1R modulating activity | UNIVERSITAT ZURICH (CH) | 2020-08-04 | — | — | US | disclosed |
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2020-07-23 | — | — | US | disclosed |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-02-25 | — | — | US | disclosed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| US-8754038-B2 | Template-fixed peptidomimetics with CCR10 antagonistic activity | POLYPHOR AG (CH) | 2014-06-17 | — | — | US | disclosed |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | CYP26A1 3133/4885KDM4E 4878/4885CYP17A1 4012/4885 |
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | BET1, BACH1, POLL | CYP26A1 4393/4885KDM4E 3588/4885CYP17A1 3339/4885 |
| US-10730911-B2 | Backbone-cyclized peptidomimetics with GLP-1R modulating activity | GLP1R, GIPR, SSTR1 | CYP26A1 3547/4885KDM4E 4766/4885CYP17A1 3980/4885 |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | CCR10, CCR1, CCRL2 | CYP26A1 3175/4885KDM4E 4722/4885CYP17A1 3715/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | CYP26A1 4329/4885KDM4E 3552/4885CYP17A1 2067/4885 |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | C1S, POLL, BACE1 | CYP26A1 3650/4885KDM4E 4764/4885CYP17A1 2307/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | CYP26A1 4193/4885KDM4E 3686/4885CYP17A1 1974/4885 |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLQ, POLL, POLM | CYP26A1 4411/4885KDM4E 4296/4885CYP17A1 2605/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | CYP26A1 3672/4885KDM4E 4761/4885CYP17A1 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.