Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633330 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL6507588 | 1.00 | — | — | |
| SCHEMBL2524053 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3422866 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2969247 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL7461021 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL18035657 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1542858 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1685840 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27497814 | 1.00 | GPR84 (0.60) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512606-A1 | NOVEL COSMETIC AND/OR NUTRACEUTICAL OR DERMATOLOGICAL USE OF A YEAST EXTRACT | BASF Beauty Care Solutions France SAS (FR) | 2019-07-24 | — | — | EP | disclosed |
| US-9060943-B2 | Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent | SYMRISE AG (DE) | 2015-06-23 | — | — | US | disclosed |
| CN-103068884-B | Photosensitive silicone resin composition | ASAHI KASEI E MATERIALS CORP | 2015-06-17 | — | — | CN | disclosed |
| CN-103068884-A | Photosensitive silicone resin composition | ASAHI KASEI E MATERIALS CORP | 2013-04-24 | — | — | CN | disclosed |
| US-8323628-B2 | Long wear cosmetic composition | L'OREAL (FR) | 2012-12-04 | — | — | US | disclosed |
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| CN-102317822-A | Polarizing plate having cured silicone coating film, and liquid crystal display device produced using same | NIPPON STEEL CHEMICAL CO | 2012-01-11 | — | — | CN | disclosed |
| US-20110123472-A1 | LONG WEAR COSMETIC COMPOSITION | L'OREAL S.A. | 2011-05-26 | — | — | US | disclosed |
| US-7855310-B2 | AH receptor antagonists | SYMRISE GMBH & CO. KG (DE) | 2010-12-21 | — | — | US | disclosed |
| CN-100545184-C | The organosilicon resin composition and the formed body thereof that contain silicon-dioxide | NIPPON STEEL CHEMICAL CO (JP) | 2009-09-30 | — | — | CN | disclosed |
| US-20090208432-A1 | AH Receptor Antagonists | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090208433-A1 | aryl hydrocarbon receptor (Ah receptor; AhR) antagonists such as 2-benzylidene-5,6-dimethoxy-3H-inden-1-one, used for preventing a translocation of an AhR into a cell nucleus, ultraviolet radiation-induced gene expression or skin damage; cosmetics; sunscreen agents; aldol condensation | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| CN-101027330-A | Silica-containing silicone resin composition and its molded product | NIPPON STEEL CHEMICAL CO (JP) | 2007-08-29 | — | — | CN | disclosed |
| US-20070166257-A1 | Long wear cosmetic composition | L'OREAL S.A. (FR) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208432-A1 | AH Receptor Antagonists | AHR, ARNT, HCAR1 | GPR84 42/4885PPARG 304/4885PPARD 362/4885 |
| US-20090208433-A1 | aryl hydrocarbon receptor (Ah receptor; AhR) antagonists such as 2-benzylidene-5,6-dimethoxy-3H-inden-1-one, used for preventing a translocation of an AhR into a cell nucleus, ultraviolet radiation-induced gene expression or skin damage; cosmetics; sunscreen agents; aldol condensation | AHR, ARNT, AIPL1 | GPR84 891/4885PPARG 58/4885PPARD 138/4885 |
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | TERT, CUTA, TRPA1 | GPR84 2110/4885PPARG 1511/4885PPARD 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.