SCHEMBL1771995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8157644	0.83	TDP1 (0.42)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL7220622	0.81	POLB (0.38)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL24065910	0.79	POLB (0.37)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL7255531	0.79	POLB (0.37)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL15920997	0.76	TDP1 (0.38)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL5356481	0.76	TDP1 (0.45)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL31075302	0.76	TDP1 (0.40)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL11235160	0.74	ALDH1A1 (0.43)	TDP1L3MBTL1ALDH1A1TSHRPOLB
	SCHEMBL4613905	0.73	TDP1 (0.50)	TDP1MEN1KMT2AL3MBTL1MAPK1
	SCHEMBL6848284	0.73	TDP1 (0.45)	TDP1MEN1KMT2AL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.