Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752895 | 0.87 | PTGES (0.41) | HTTPDE4BTDP1NT5EMAPT | |
| SCHEMBL515743 | 0.87 | HTT (0.50) | HTTPDE4BMAOAMAOBNT5E | |
| SCHEMBL516091 | 0.80 | TDP1 (0.59) | HTTPDE4BMAOAMAOBTDP1 | |
| SCHEMBL3503005 | 0.79 | KMT2A (0.45) | HTTKMT2ARXFP1MEN1GPR3 | |
| SCHEMBL12481032 | 0.79 | MAOA (0.44) | MAOAMAOBTDP1KDM4EPKM | |
| SCHEMBL29539036 | 0.79 | GPR3 (0.66) | HTTKMT2ARXFP1MEN1GPR3 | |
| SCHEMBL28538059 | 0.77 | KMT2A (0.52) | HTTPDE4BMAOAMAOBKDM4E | |
| SCHEMBL4163817 | 0.76 | MAOA (0.67) | HTTMAOAMAOBTDP1KDM4E | |
| SCHEMBL3856320 | 0.76 | MAOA (0.67) | HTTMAOAMAOBTDP1KDM4E | |
| SCHEMBL18647353 | 0.74 | PRNP (0.55) | KMT2ARXFP1MEN1MAPTPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218368-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-10577342-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-03-03 | — | — | US | disclosed |
| WO-2016074755-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577342-B2 | Materials for organic electroluminescent devices | PIEZO1, L1CAM, EFNA1 | HTT 2472/4885PDE4B 4386/4885MAOA 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.