SCHEMBL177573

SCHEMBL177573

Fc1cc(F)cc(OBOc2cc(F)cc(F)c2)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
IDO1 P14902 2/20 0.33
SOD1 P00441 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622877 0.83 ACHE (0.34)
SCHEMBL3716120 0.83 CA12 (0.52) CA12CA1CA9
SCHEMBL15416416 0.83 VEGFA (0.32)
SCHEMBL4043764 0.83 ALDH1A1 (0.50) CYP1A2CYP2A6
SCHEMBL874186 0.83 EPAS1 (0.38)
SCHEMBL1128558 0.79 SCN9A (0.35) IDO1SOD1CES2
SCHEMBL3439551 0.78 CA12 (0.39) CA12CA1CA9IDO1SOD1
SCHEMBL4048298 0.78 FGFR1 (0.40) SOD1CYP1A2
SCHEMBL1584993 0.78 EPAS1 (0.40)
SCHEMBL170454 0.74 NFE2L2 (0.41) IDO1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228437-A1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-11 US claimed
CN-117529470-A Method for producing pyrrolidine compounds 武田药品工业株式会社 2024-02-06 CN claimed
US-11495769-B2 Inorganic light emitting diode and inorganic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2022-11-08 US claimed
US-20210167321-A1 INORGANIC LIGHT EMITTING DIODE AND INORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-06-03 US claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
US-12600709-B2 Nonpeptide somatostatin type 5 receptor agonists and uses thereof Crinetics Pharmaceuticals, Inc. (US) 2026-04-14 US disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260008767-A1 SOMATOSTATIN MODULATORS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2026-01-08 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
EP-3909964-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-10-08 EP disclosed
EP-4608808-A1 SOMATOSTATIN RECEPTOR 2 AGONISTS AND USES THEREOF Basecamp Bio Inc. (KY) 2025-09-03 EP disclosed
EP-4043500-B1 ETHYLENE·ALPHA-OLEFIN·NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS INC (JP) 2025-08-13 EP disclosed
US-6667319-B2 Benzyl-cyclohexyl-uredo-p-piperidinyl amido- or sulfamido-derivatives; obesity, metabolic disorders, eating disorders SCHERING-PLOUGH CORPORATION 2003-12-23 US disclosed
US-20030225110-A1 Tetrahydroquinoline derivatives as antithrombotic agents BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-12-04 US disclosed
US-20030207860-A1 Neuropeptide Y Y5 receptor antagonists SCHERING CORPORATION 2003-11-06 US disclosed
US-6593493-B1 2-(Carboxy(unsaturated)alkyl)-1-(haloalkoxy)benzene derivatives; retinoid X receptors; cardiovascular, skin, eating and vision disorders; anticarcinogenic agents; non-insulin-dependent diabetes LIGAND PHARMACEUTICALS, INC. 2003-07-15 US disclosed
WO-2003009845-A1 SUBSTITUTED UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-02-06 WO disclosed
EP-1216221-A2 RXR MODULATORS WITH IMPROVED PHARMACOLOGIC PROFILE LIGAND PHARMACEUTICALS INCORPORATED (US) 2002-06-26 EP disclosed
WO-2002039997-A2 ACE-2 MODULATING COMPOUNDS AND USE THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-05-23 WO disclosed
WO-2001019770-A2 RXR MODULATORS WITH IMPROVED PHARMACOLOGIC PROFILE LIGAND PHARMACEUTICALS INCORPORATED (US) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225110-A1 Tetrahydroquinoline derivatives as antithrombotic agents TFPI, TFPI2, SERPINC1 CA12 3465/4885CA1 1448/4885CA9 2946/4885
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B CA12 1457/4885CA1 976/4885CA9 732/4885
US-20240228437-A1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND PAH, SPR, IL4I1 CA12 2941/4885CA1 3104/4885CA9 604/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 CA12 522/4885CA1 701/4885CA9 339/4885
US-20030207860-A1 Neuropeptide Y Y5 receptor antagonists NPY5R, NPY1R, NPY2R CA12 4142/4885CA1 4216/4885CA9 2146/4885
US-12600709-B2 Nonpeptide somatostatin type 5 receptor agonists and uses thereof SSTR5, SSTR4, GLP1R CA12 1927/4885CA1 2253/4885CA9 1314/4885
US-20260008767-A1 SOMATOSTATIN MODULATORS AND USES THEREOF SSTR5, SSTR3, SSTR2 CA12 256/4885CA1 260/4885CA9 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.