SCHEMBL1775975

SCHEMBL1775975

CC1COC(C)(c2ccc3c(c2)C(C)(C)CCC3(C)C)O1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RXRA P19793 14/20 0.43
RXRB P28702 8/20 0.43
CYP26A1 O43174 7/20 0.43
CYP26B1 Q9NR63 7/20 0.43
RXRG P48443 7/20 0.41
RARB P10826 4/20 0.41
RARA P10276 3/20 0.41
RARG P13631 3/20 0.41
PPARG P37231 1/20 0.41
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794870 1.00 RXRA (0.43) RXRARXRBCYP26A1CYP26B1RXRG
SCHEMBL9501274 0.85 RXRA (0.44) RXRARXRBCYP26A1CYP26B1RXRG
SCHEMBL9498190 0.82 RXRA (0.41) RXRARXRBCYP26A1CYP26B1RXRG
SCHEMBL9876435 0.74 CHRNA1 (0.45)
SCHEMBL10839765 0.72 ESR2 (0.41)
SCHEMBL7520074 0.72 RXRA (0.54) RXRARXRBCYP26A1CYP26B1RXRG
SCHEMBL5156026 0.72 CHRNB2 (0.40)
SCHEMBL8340501 0.70 RXRA (0.52) RXRARXRBCYP26A1CYP26B1RXRG
SCHEMBL6293972 0.69 HCRTR1 (0.32)
SCHEMBL18857047 0.68 USP2 (0.47) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
EP-4446001-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2024-10-16 EP claimed
EP-4407019-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2024-07-31 EP claimed
US-20240173230-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-05-30 US claimed
US-20230151305-A1 FRAGRANCE COMPOSITION SA, GIVAUDAN (CH) 2023-05-18 US claimed
EP-4146778-A1 FRAGRANCE COMPOSITION Givaudan SA (CH) 2023-03-15 EP claimed
CN-115551986-A Fragrance composition 奇华顿股份有限公司 2022-12-30 CN claimed
US-11364184-B2 Perfume compositions GIVAUDAN SA (CH) 2022-06-21 US claimed
EP-3295925-B2 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR NOXELL CORP (US) 2022-05-18 EP claimed
US-11332693-B2 Organic compounds GIVAUDAN SA (CH) 2022-05-17 US claimed
WO-2016049394-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049396-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
EP-1894603-B1 Encapsulation of bulky fragrance molecules TAKASAGO PERFUMERY CO LTD (JP) 2014-11-19 EP claimed
EP-1737937-B1 PERFUME COMPOSITIONS GIVAUDAN NEDERLAND SERVICES BV (NL) 2013-06-12 EP claimed
US-7781392-B2 Perfume compositions QUEST INTERNATIONAL SERVICES B.V. (NL) 2010-08-24 US claimed
US-20070287659-A1 Perfume Compositions QUEST INTERNATIONAL SERVICES B.V. (NL) 2007-12-13 US claimed
WO-1998056337-A1 MALODOR REDUCING COMPOSITION CONTAINING AMBER AND MUSK MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1998-12-17 WO claimed
EP-0379981-B1 ACETALES OF OXO-TETRALINES AND OF OXO-INDANES L. GIVAUDAN & CIE Société Anonyme (CH) 1993-04-07 EP claimed
US-5084440-A Deodorizing compounds GIVAUDAN CORPORATION (US) 1992-01-28 US claimed
EP-0379981-A1 Acetales of oxo-tetralines and of oxo-indanes L. GIVAUDAN & CIE Société Anonyme (CH) 1990-08-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559703-B2 Fragrance composition DHCR24, OPRD1, OR10J3 RXRA 1508/4885RXRB 1327/4885CYP26A1 331/4885
US-20240173230-A1 FRAGRANCE COMPOSITION FABP2, FABP5, FAAH2 RXRA 251/4885RXRB 288/4885CYP26A1 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.