Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.44 |
| ▸ | RXRB | P28702 | 9/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 7/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775975 | 0.85 | RXRA (0.43) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL29364461 | 0.85 | RXRA (0.43) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL3794870 | 0.85 | RXRA (0.43) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL9498190 | 0.74 | RXRA (0.41) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL7255673 | 0.72 | OPRK1 (0.41) | — | |
| SCHEMBL8340501 | 0.68 | RXRA (0.52) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL6239341 | 0.67 | RXRA (0.45) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL6240236 | 0.67 | RXRA (0.45) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL20122006 | 0.66 | RXRA (0.68) | RXRARXRBCYP26A1CYP26B1CYP3A4 | |
| SCHEMBL10888704 | 0.66 | CA2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379981-B1 | ACETALES OF OXO-TETRALINES AND OF OXO-INDANES | L. GIVAUDAN & CIE Société Anonyme (CH) | 1993-04-07 | — | — | EP | claimed |
| US-5084440-A | Deodorizing compounds | GIVAUDAN CORPORATION (US) | 1992-01-28 | — | — | US | claimed |
| EP-0379981-A1 | Acetales of oxo-tetralines and of oxo-indanes | L. GIVAUDAN & CIE Société Anonyme (CH) | 1990-08-01 | — | — | EP | claimed |
| EP-0379981-B1 | ACETALES OF OXO-TETRALINES AND OF OXO-INDANES | L. GIVAUDAN & CIE Société Anonyme (CH) | 1993-04-07 | — | — | EP | disclosed |
| US-5084440-A | Deodorizing compounds | GIVAUDAN CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0379981-A1 | Acetales of oxo-tetralines and of oxo-indanes | L. GIVAUDAN & CIE Société Anonyme (CH) | 1990-08-01 | — | — | EP | disclosed |