SCHEMBL17779502

SCHEMBL17779502

Cc1cc(-c2cccc(-c3ccccc3)c2)nc(-c2ccccc2)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
KMT2A Q03164 8/20 0.51
MEN1 O00255 7/20 0.51
MAPT P10636 6/20 0.51
ABCG2 Q9UNQ0 5/20 0.51
HPGD P15428 4/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPK1 P28482 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
ATM Q13315 1/20 0.51
NPC1 O15118 1/20 0.47
GBA1 P04062 1/20 0.47
RAB9A P51151 1/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
GLA P06280 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922596 0.98 LMNA (0.56) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL16922527 0.96 LMNA (0.53) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL18731969 0.93 LMNA (0.53) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL21031210 0.91 LMNA (0.51) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL22376265 0.91 LMNA (0.49) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL18934510 0.90 L3MBTL1 (0.52) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL25491455 0.89 LMNA (0.61) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL16373471 0.89 LMNA (0.61) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL16376450 0.89 LMNA (0.61) LMNAKMT2AMEN1MAPTABCG2
SCHEMBL16922505 0.89 LMNA (0.61) LMNAKMT2AMEN1MAPTABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11659765-B2 Composition for organic optoelectronic element, organic optoelectronic element, and display device SAMSUNG SDI CO., LTD. (KR) 2023-05-23 US disclosed
US-11653564-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-05-16 US disclosed
US-11653564-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-05-16 US disclosed
EP-3992190-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DIODE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2022-05-04 EP disclosed
EP-3483152-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-04-28 EP disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
US-10738034-B2 Spiro compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2020-08-11 US disclosed
US-20200131204-A1 SILICON-CONTAINING ELECTRON TRANSPORTING MATERIAL AND ITS APPLICATION Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-04-30 US disclosed
EP-3345982-B1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-03-18 EP disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed
EP-3345982-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-11 EP disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
WO-2017061810-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2017-04-13 WO disclosed
US-20160285009-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-29 US disclosed
US-20160218299-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-28 US disclosed
US-20160218299-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-28 US disclosed
WO-2016079667-A1 INDOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS IDEMITSU KOSAN CO., LTD. (JP) 2016-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738034-B2 Spiro compound and organic light-emitting device comprising same CRY1, NR2E3, ERG LMNA 3057/4885KMT2A 1480/4885MEN1 611/4885
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 LMNA 3427/4885KMT2A 719/4885MEN1 1825/4885
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG LMNA 3057/4885KMT2A 1480/4885MEN1 611/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 LMNA 2539/4885KMT2A 1221/4885MEN1 3802/4885
US-20160218299-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EFNA1, L1CAM, LEF1 LMNA 1243/4885KMT2A 1923/4885MEN1 842/4885
US-11653564-B2 Compound and organic light-emitting device comprising same CRY1, CYP1A1, TMEM109 LMNA 3110/4885KMT2A 1084/4885MEN1 289/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 LMNA 2539/4885KMT2A 1221/4885MEN1 3802/4885
US-20160285009-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND LMNA 3369/4885KMT2A 3021/4885MEN1 4134/4885
US-20200131204-A1 SILICON-CONTAINING ELECTRON TRANSPORTING MATERIAL AND ITS APPLICATION SLCO4C1, SLC35E1, SLC2A9 LMNA 2088/4885KMT2A 3723/4885MEN1 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.