Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022797 | 0.79 | HNF4A (0.41) | CA12CA2CA9GPR84KDM4E | |
| SCHEMBL16772619 | 0.76 | ERN1 (0.39) | ERN1SIRT2SIRT1CYP2A6AHR | |
| SCHEMBL12022793 | 0.76 | CA1 (0.41) | CA2GPR84KDM4E | |
| SCHEMBL3568497 | 0.75 | MAPT (0.52) | ERN1SIRT2SIRT1CYP2A6AHR | |
| SCHEMBL3561759 | 0.75 | SIRT2 (0.40) | ERN1SIRT2SIRT1CYP2A6AHR | |
| SCHEMBL1777121 | 0.74 | GPR84 (0.53) | CA12CA9SIRT1CYP2A6GPR84 | |
| SCHEMBL30901145 | 0.74 | GPR84 (0.53) | CA12CA9SIRT1CYP2A6GPR84 | |
| SCHEMBL297640 | 0.73 | GPR84 (0.62) | ERN1SIRT2SIRT1NCEH1GPR84 | |
| SCHEMBL12600563 | 0.73 | CYP1A1 (0.50) | GPR84 | |
| SCHEMBL3565631 | 0.72 | MAPT (0.44) | ERN1SIRT2SIRT1CYP2A6AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004622-B1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| EP-2004622-B1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7943061-B2 | Chiral binaphthyl sulfates for use as liquid crystal materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-7943061-B2 | Chiral binaphthyl sulfates for use as liquid crystal materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-7943061-B2 | Chiral binaphthyl sulfates for use as liquid crystal materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-28 | — | — | US | disclosed |
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-28 | — | — | US | disclosed |
| EP-2004622-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | Merck Patent GmbH (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007124383-A2 | 1,1'-BINAPHTHYL-BASED INHIBITORS OF NAD+-DEPENDENT DEACETYLASE ACTIVITY AND SIR2-FAMILY MEMBERS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007115639-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115639-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | DVL3, DVL1, EBPL | CA12 591/4885CA2 3971/4885CA9 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.