SCHEMBL17784281

SCHEMBL17784281

C=C(C)C(=O)NCC1(C)OCCO1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32
POLB P06746 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24674956 0.75 OPRM1 (0.41) TGFBR1
SCHEMBL10962418 0.74 SMN1; SMN2 (0.39) KMT2ASMN1; SMN2
SCHEMBL10964399 0.73 ALDH1A2 (0.39) KMT2A
SCHEMBL16181328 0.73 LMNA (0.46) L3MBTL1KMT2A
Methacrylic Acid SCHEMBL15739028 0.69
SCHEMBL16181329 0.69 TSHR (0.40) POLBRECQLKMT2ASMN1; SMN2
SCHEMBL6825744 0.68 ALDH1A1 (0.35) TGFBR1POLBRECQLBLML3MBTL1
SCHEMBL316224 0.68 TGFBR1 (0.41) TGFBR1SMN1; SMN2
SCHEMBL59411 0.68 TGFBR1 (0.41) TGFBR1
SCHEMBL14949 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109821-A1 SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF UNIV MCMASTER (CA) 2026-04-23 US claimed
US-12359026-B2 In situ gelling zwitterionic hydrogel compositions, and methods of use thereof MCMASTER UNIVERSITY (CA) 2025-07-15 US claimed
US-20230220166-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2023-07-13 US claimed
EP-4153664-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF McMaster University (CA) 2023-03-29 EP claimed
WO-2021237369-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2021-12-02 WO claimed
US-10363340-B2 Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof MCMASTER UNIVERSITY (CA) 2019-07-30 US claimed
US-20160151535-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2016-06-02 US claimed
US-20260109821-A1 SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF UNIV MCMASTER (CA) 2026-04-23 US disclosed
US-12359026-B2 In situ gelling zwitterionic hydrogel compositions, and methods of use thereof MCMASTER UNIVERSITY (CA) 2025-07-15 US disclosed
US-20230220166-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2023-07-13 US disclosed
US-20230220166-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2023-07-13 US disclosed
US-20230220166-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2023-07-13 US disclosed
EP-4153664-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF McMaster University (CA) 2023-03-29 EP disclosed
WO-2021237369-A1 IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2021-12-02 WO disclosed
US-20200256860-A1 PRINTABLE HYDROGELS FOR BIOMOLECULE IMMOBILIZATION AND STABILIZATION MCMASTER UNIVERSITY (CA) 2020-08-13 US disclosed
US-20190321512-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2019-10-24 US disclosed
US-20190321512-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2019-10-24 US disclosed
US-10363340-B2 Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof MCMASTER UNIVERSITY (CA) 2019-07-30 US disclosed
US-20160151535-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2016-06-02 US disclosed
US-20160151535-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2016-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109821-A1 SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF ITGA1, ITGB1, F12 TGFBR1 122/4885POLB 3257/4885RECQL 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.