SCHEMBL17796149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7813902	0.86	GABRP (0.47)	SIRT6GABRPGABRDGABRA1GABRB1
	SCHEMBL17362420	0.86	SIRT6 (0.47)	SIRT6SLC9A1GABRPGABRDGABRA1
	SCHEMBL26765951	0.84	GABRP (0.38)	SIRT6GABRPGABRDGABRA1GABRB1
	SCHEMBL29977172	0.80	ABL1 (0.56)	ABL1KDM4EALDH1A1LMNAMAPT
	SCHEMBL4499056	0.80	ABL1 (0.56)	ABL1KDM4EALDH1A1LMNAMAPT
	SCHEMBL18929978	0.80	NNMT (0.41)	NNMTABL1
	SCHEMBL16333365	0.78	NNMT (0.42)	SIRT6NNMTNAPRTHAVCR2KDM4E
	SCHEMBL29577063	0.78	NNMT (0.42)	SIRT6NNMTNAPRTHAVCR2KDM4E
	SCHEMBL25426252	0.77	SIRT2 (0.33)	—
	SCHEMBL22117169	0.76	TDP1 (0.33)	GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.