Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800696 | 0.78 | LPL (0.38) | LPLLIPG | |
| SCHEMBL17800667 | 0.72 | P2RX7 (0.30) | — | |
| SCHEMBL17800690 | 0.72 | P2RX7 (0.37) | LPLLIPG | |
| SCHEMBL17800708 | 0.70 | — | — | |
| SCHEMBL17800698 | 0.70 | — | — | |
| SCHEMBL51973 | 0.70 | KMT2A (0.34) | — | |
| SCHEMBL17800648 | 0.69 | LPL (0.38) | LPLLIPG | |
| Fluoride SCHEMBL27794969 | 0.68 | KMT2A (0.33) | — | |
| Iodide SCHEMBL28487528 | 0.68 | KMT2A (0.33) | — | |
| SCHEMBL30851281 | 0.68 | LPL (0.40) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862732-B2 | Regioselective 1,2-dearomatization of functionalized azines by organolanthanide catalysts | NORTHWESTERN UNIVERSITY (US) | 2018-01-09 | — | — | US | claimed |
| US-20160159825-A1 | Regioselective 1,2-Dearomatization of Functionalized Azines by Organolanthanide Catalysts | NATIONAL SCIENCE FOUNDATION | 2016-06-09 | — | — | US | claimed |
| US-11851408-B2 | Method for preparing pyridine compound substituted with trifluoromethylthio, difluoromethylthio or trifluoromethyl in meta position | NANKAI UNIVERSITY (CN) | 2023-12-26 | — | — | US | disclosed |
| US-20230365502-A1 | METHOD FOR PREPARING PYRIDINE COMPOUND SUBSTITUTED WITH TRIFLUOROMETHYLTHIO, DIFLUOROMETHYLTHIO OR TRIFLUOROMETHYL IN META POSITION | NANKAI UNIVERSITY (CN) | 2023-11-16 | — | — | US | disclosed |
| US-9862732-B2 | Regioselective 1,2-dearomatization of functionalized azines by organolanthanide catalysts | NORTHWESTERN UNIVERSITY (US) | 2018-01-09 | — | — | US | disclosed |
| US-20160159825-A1 | Regioselective 1,2-Dearomatization of Functionalized Azines by Organolanthanide Catalysts | NATIONAL SCIENCE FOUNDATION | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851408-B2 | Method for preparing pyridine compound substituted with trifluoromethylthio, difluoromethylthio or trifluoromethyl in meta position | TDO2, DPM1, FBXL19 | LPL 4125/4885LIPG 4108/4885 |
| US-20160159825-A1 | Regioselective 1,2-Dearomatization of Functionalized Azines by Organolanthanide Catalysts | DERL1, AZI2, AOC2 | LPL 1382/4885LIPG 3254/4885 |
| US-20230365502-A1 | METHOD FOR PREPARING PYRIDINE COMPOUND SUBSTITUTED WITH TRIFLUOROMETHYLTHIO, DIFLUOROMETHYLTHIO OR TRIFLUOROMETHYL IN META POSITION | TDO2, DPM1, FBXL19 | LPL 4125/4885LIPG 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.