Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 15/20 | 0.41 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13280599 | 0.82 | GAA (0.41) | EZH2TSHRALDH1A1HPGD | |
| SCHEMBL13468049 | 0.82 | EZH2 (0.39) | EZH2TSHRALDH1A1HPGD | |
| SCHEMBL17804334 | 0.81 | PDK1 (0.35) | EZH2TCF4CTNNB1TSHRALDH1A1 | |
| SCHEMBL18829845 | 0.80 | ALDH1A1 (0.41) | EZH2TSHRALDH1A1HPGD | |
| SCHEMBL15710441 | 0.79 | MEN1 (0.40) | EZH2TSHRALDH1A1 | |
| SCHEMBL13468019 | 0.78 | LMNA (0.39) | EZH2TCF4CTNNB1TSHRALDH1A1 | |
| SCHEMBL13280720 | 0.78 | EZH2 (0.40) | EZH2TSHRALDH1A1 | |
| SCHEMBL13280289 | 0.77 | MEN1 (0.41) | EZH2TSHRALDH1A1HPGD | |
| SCHEMBL17804350 | 0.76 | EZH2 (0.55) | EZH2 | |
| SCHEMBL17804325 | 0.75 | EZH2 (0.42) | EZH2TSHRALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |