SCHEMBL17808142

SCHEMBL17808142

c1ccc(-c2cccc(-c3cc(-c4ccc(-c5cccnc5)cc4)nc(-c4cccc(-c5cccc6ccccc56)c4)n3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.49
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 4/20 0.49
MAPT P10636 4/20 0.49
HPGD P15428 4/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP19A1 P11511 2/20 0.47
CYP11B1 P15538 2/20 0.47
CYP17A1 P05093 1/20 0.47
CYP11B2 P19099 1/20 0.47
TNF P01375 1/20 0.46
KMO O15229 1/20 0.44
MEN1 O00255 2/20 0.43
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP2C9 P11712 2/20 0.42
GLA P06280 2/20 0.40
GAA P10253 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17807973 1.00 DHODH (0.49) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL17918046 0.97 KDM4E (0.51) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL17808049 0.97 KDM4E (0.51) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL19650653 0.97 KDM4E (0.51) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL30297006 0.97 KDM4E (0.51) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL19397481 0.96 ALDH1A1 (0.50) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL17808146 0.95 DHODH (0.49) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL17917888 0.95 DHODH (0.49) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL30296872 0.95 DHODH (0.49) DHODHKDM4EALDH1A1MAPTHPGD
SCHEMBL19397428 0.95 ALDH1A1 (0.54) DHODHKDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
EP-3244463-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-07-22 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-20190273216-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-05 US disclosed
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode HODOGAYA CHEMICAL CO., LTD. (JP) 2019-04-30 US disclosed
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-01-03 US disclosed
EP-3291323-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2018-03-07 EP disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode SLC29A1, SLC29A2, NUDT1 DHODH 290/4885KDM4E 1989/4885ALDH1A1 776/4885
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 DHODH 2619/4885KDM4E 1822/4885ALDH1A1 228/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT DHODH 1866/4885KDM4E 1225/4885ALDH1A1 599/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD DHODH 8/4885KDM4E 1255/4885ALDH1A1 329/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD DHODH 8/4885KDM4E 1255/4885ALDH1A1 329/4885
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLC7A5, SLCO4C1 DHODH 1638/4885KDM4E 1071/4885ALDH1A1 227/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 DHODH 241/4885KDM4E 2113/4885ALDH1A1 357/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 DHODH 255/4885KDM4E 1478/4885ALDH1A1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.