SCHEMBL17808147

SCHEMBL17808147

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5cccnc5)c4)nc(-c4ccc(-c5cccc6ccccc56)cc4)n3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
RAB9A P51151 1/20 0.50
TNF P01375 1/20 0.50
CYP19A1 P11511 2/20 0.48
CYP11B1 P15538 2/20 0.48
CYP17A1 P05093 1/20 0.48
CYP11B2 P19099 1/20 0.48
DHODH Q02127 1/20 0.47
KMO O15229 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CYP2C9 P11712 3/20 0.42
TSHR P16473 3/20 0.42
MEN1 O00255 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17808146 0.99 DHODH (0.49) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL30296872 0.99 DHODH (0.49) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL17917888 0.99 DHODH (0.49) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL23095095 0.97 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL17917871 0.97 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL23095099 0.96 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL19397481 0.95 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL30296922 0.95 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL17808138 0.95 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL19637994 0.95 TNF (0.52) ALDH1A1MAPTKDM4EHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
EP-3754739-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2020-12-23 EP disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
EP-3244463-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-07-22 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-20190273216-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-05 US disclosed
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-01-03 US disclosed
EP-3291323-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2018-03-07 EP disclosed
US-20170346015-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-30 US disclosed
US-20170346015-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-30 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 ALDH1A1 228/4885MAPT 2734/4885KDM4E 1822/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT ALDH1A1 599/4885MAPT 2246/4885KDM4E 1225/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD ALDH1A1 329/4885MAPT 2393/4885KDM4E 1255/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD ALDH1A1 329/4885MAPT 2393/4885KDM4E 1255/4885
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLC7A5, SLCO4C1 ALDH1A1 227/4885MAPT 1328/4885KDM4E 1071/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 ALDH1A1 357/4885MAPT 2401/4885KDM4E 2113/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 ALDH1A1 633/4885MAPT 2430/4885KDM4E 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.