Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 5/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242574 | 0.90 | CHRNA7 (0.40) | HTR3ACHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL3756715 | 0.88 | CHRNA7 (0.40) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL503793 | 0.72 | CHRNA7 (0.40) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL235246 | 0.72 | HTR3A (0.52) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL504169 | 0.72 | HTR3A (0.52) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL6229642 | 0.70 | CHRNA7 (0.37) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL1783138 | 0.70 | ALKBH1 (0.48) | KCNH2 | |
| SCHEMBL5109993 | 0.69 | CHRNB2 (0.44) | HTR3ACHRNA7KCNH2 | |
| SCHEMBL5112722 | 0.69 | CHRM2 (0.39) | CHRNA7 | |
| SCHEMBL3247883 | 0.69 | GRIN2D (0.40) | HTR3ACHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118268-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-05-19 | — | — | US | disclosed |
| EP-2262810-A2 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NeuroSearch A/S (DK) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009112462-A2 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118268-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | CHRNA6, CHRNA2, CHRNA10 | FURIN 4718/4885HTR3A 69/4885CHRNA7 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.