Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 known ✓ | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 known ✓ | Q07820 | 1/20 | 0.41 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 8/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL27686988 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Diphenylsulfane SCHEMBL28815911 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Diphenylsulfane SCHEMBL27852555 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Trifluoromethanesulfonic Acid SCHEMBL17835417 | 0.84 | MMP13 (0.41) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| SCHEMBL544383 | 0.83 | MAOA (0.50) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| SCHEMBL25895028 | 0.83 | MAOA (0.50) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Hydrochloric Acid SCHEMBL9007558 | 0.81 | MAOA (0.48) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Benzenethiol SCHEMBL28177073 | 0.81 | KEAP1 (0.46) | ALDH1A1HPGDMMP13MMP8MMP2 | |
| Phosphoric Acid SCHEMBL28683981 | 0.80 | HPGD (0.47) | ALDH1A1HPGDMMP13MMP8MMP3 | |
| Fluoride SCHEMBL27764069 | 0.79 | MAOA (0.46) | ALDH1A1HPGDMMP13MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982049-B2 | Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide | DIC CORPORATION (JP) | 2021-04-20 | — | — | US | disclosed |
| EP-3042924-B1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DAINIPPON INK & CHEMICALS (JP) | 2020-04-29 | — | — | EP | disclosed |
| EP-3636632-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENESULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DIC Corporation (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20190300652-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DAINIPPON INK & CHEMICALS (JP) | 2019-10-03 | — | — | US | disclosed |
| US-10385168-B2 | Polyarylene sulfide resin and manufacturing method therefor, poly(arylenesulfonium salt) and manufacturing method therefor, and sulfoxide | DIC CORPORATION (JP) | 2019-08-20 | — | — | US | disclosed |
| EP-3034542-B1 | POLYARYLENE SULFIDE RESIN, MANUFACTURING METHOD THEREFOR, AND MOLDING | DAINIPPON INK & CHEMICALS (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-10072124-B2 | Polyarylene sulfide resin, manufacturing method therefor, and molding | DIC CORPORATION (JP) | 2018-09-11 | — | — | US | disclosed |
| US-20170218125-A1 | POLYARYLENE SULFIDE RESIN, MANUFACTURING METHOD THEREFOR, AND MOLDING | DAINIPPON INK & CHEMICALS (JP) | 2017-08-03 | — | — | US | disclosed |
| US-20170218126-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DAINIPPON INK & CHEMICALS (JP) | 2017-08-03 | — | — | US | disclosed |
| US-9657142-B2 | Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide | DIC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160200874-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DIC CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| EP-3042924-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DIC Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| EP-3034542-A1 | POLYARYLENE SULFIDE RESIN, MANUFACTURING METHOD THEREFOR, AND MOLDING | DIC Corporation (JP) | 2016-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300652-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | GARS1, ASH2L, SULT1A1 | BCL2 3726/4885MCL1 3046/4885MAOB 3981/4885 |
| US-20160200874-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | GARS1, ASH2L, SULT1A1 | BCL2 3726/4885MCL1 3046/4885MAOB 3981/4885 |
| US-10982049-B2 | Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide | GARS1, ASH2L, SULT1A1 | BCL2 3726/4885MCL1 3046/4885MAOB 3981/4885 |
| US-20170218126-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | GARS1, ASH2L, SULT1A1 | BCL2 3726/4885MCL1 3046/4885MAOB 3981/4885 |
| US-10385168-B2 | Polyarylene sulfide resin and manufacturing method therefor, poly(arylenesulfonium salt) and manufacturing method therefor, and sulfoxide | GARS1, ASH2L, SULT1A1 | BCL2 3756/4885MCL1 2910/4885MAOB 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.