SCHEMBL1783988

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16471130	0.84	AKR1C2 (0.43)	KDM4ESMN1; SMN2MAPTLMNANPC1
	SCHEMBL276547	0.82	PTPN1 (0.46)	KDM4ESMN1; SMN2ESR2MAOBMAOA
	SCHEMBL1484281	0.82	ALDH1A1 (0.43)	KDM4ESMN1; SMN2MAPTKMT2AMEN1
	SCHEMBL1784106	0.81	PTGS1 (0.48)	SMN1; SMN2MAOBMAOAMAPTKMT2A
	SCHEMBL280393	0.81	MAPT (0.53)	KDM4ESMN1; SMN2MAPTKMT2AMEN1
	SCHEMBL12755577	0.81	ERN1 (0.37)	KDM4EESR2HSD17B1HSD17B2KMT2A
	SCHEMBL278084	0.76	MCL1 (0.44)	KDM4ESMN1; SMN2MAOBHSD17B1MAPT
	SCHEMBL277337	0.75	ABL1 (0.44)	KDM4EMAPTKMT2AMEN1LMNA
	SCHEMBL8404738	0.73	RAB9A (0.48)	KDM4ESMN1; SMN2MAPTNPC1HPGD
	SCHEMBL277402	0.72	ALAD (0.39)	KDM4ESMN1; SMN2MAOBMAOACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.