Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NRP1 | O14786 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | FES | P07332 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844229 | 0.87 | MEN1 (0.48) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL5306584 | 0.84 | NTRK1 (0.38) | EPHX2HCRTR1HCRTR2FFAR1FFAR4 | |
| SCHEMBL17844151 | 0.81 | PIM1 (0.39) | KDM4ECHRM5 | |
| SCHEMBL17844217 | 0.79 | CXCR2 (0.36) | — | |
| SCHEMBL17844247 | 0.77 | HTR1B (0.39) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL17844246 | 0.76 | HCRTR1 (0.39) | MEN1KMT2APOLBHCRTR1HCRTR2 | |
| SCHEMBL5186747 | 0.75 | PTPN2 (0.37) | POLB | |
| SCHEMBL17844227 | 0.74 | POLB (0.39) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL17844178 | 0.74 | DRD4 (0.43) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL17844232 | 0.71 | DRD2 (0.44) | KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |