Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844247 | 0.88 | HTR1B (0.39) | KDM4E | |
| SCHEMBL17844212 | 0.87 | MTNR1A (0.42) | KDM4E | |
| SCHEMBL17844217 | 0.86 | CXCR2 (0.36) | PIM1DYRK1ATRPC5 | |
| SCHEMBL17844169 | 0.85 | SCN9A (0.36) | HDAC1HDAC2KDM4E | |
| SCHEMBL17844232 | 0.85 | DRD2 (0.44) | HDAC1HDAC2KDM4E | |
| SCHEMBL17844230 | 0.83 | DRD2 (0.46) | KDM4E | |
| SCHEMBL5186747 | 0.81 | PTPN2 (0.37) | HDAC1HDAC2 | |
| SCHEMBL17844105 | 0.81 | LTA4H (0.41) | CHRM5KDM4E | |
| SCHEMBL17844246 | 0.80 | HCRTR1 (0.39) | HDAC1HDAC2KDM4E | |
| SCHEMBL5306584 | 0.78 | NTRK1 (0.38) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |