Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844227 | 0.79 | POLB (0.39) | KDM4ELMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17844110 | 0.77 | MAOA (0.40) | KMT2A | |
| SCHEMBL17844229 | 0.76 | MEN1 (0.48) | KDM4ELMNAHTTALDH1A1CASP3 | |
| SCHEMBL17844139 | 0.75 | FDPS (0.36) | CYP1A2CYP2D6ALDH1A1CASP3SMN1; SMN2 | |
| SCHEMBL17844176 | 0.74 | ADORA3 (0.35) | CYP3A4CYP2D6GABRA5 | |
| SCHEMBL17844232 | 0.73 | DRD2 (0.44) | KDM4E | |
| SCHEMBL17844236 | 0.73 | DRD2 (0.44) | KDM4ELMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL17844244 | 0.73 | MTNR1A (0.40) | KDM4ELMNAALDH1A1 | |
| SCHEMBL3551960 | 0.73 | BRD4 (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL17844148 | 0.72 | KMT2A (0.40) | KDM4EHTTALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |