Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844249 | 0.84 | ACHE (0.50) | MAPTACHEBCHE | |
| SCHEMBL17844206 | 0.80 | NPC1 (0.41) | GRIN1GRIN2BGABRA5MAPTRECQL | |
| SCHEMBL17844171 | 0.79 | MALT1 (0.47) | ACHEBCHE | |
| SCHEMBL17844164 | 0.78 | KAT2B (0.38) | — | |
| SCHEMBL17844160 | 0.78 | SIGMAR1 (0.45) | ACHEBCHE | |
| SCHEMBL1996993 | 0.74 | NR1H2 (0.44) | PRKAA2GRIN1GRIN2BGABRA5MAPT | |
| SCHEMBL5184355 | 0.74 | BRD4 (0.36) | — | |
| SCHEMBL17844153 | 0.72 | MAPK8 (0.41) | MAPT | |
| SCHEMBL3546550 | 0.72 | LMNA (0.42) | — | |
| SCHEMBL17844145 | 0.71 | HRH3 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |