Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184355 | 0.76 | BRD4 (0.36) | — | |
| SCHEMBL17844229 | 0.74 | MEN1 (0.48) | — | |
| SCHEMBL17844227 | 0.73 | POLB (0.39) | — | |
| SCHEMBL1999234 | 0.72 | NR1H2 (0.45) | PARP14DNMT1DNMT3B | |
| SCHEMBL3551960 | 0.71 | BRD4 (0.39) | — | |
| SCHEMBL17844110 | 0.71 | MAOA (0.40) | — | |
| SCHEMBL17844119 | 0.70 | TAAR1 (0.40) | — | |
| SCHEMBL5184298 | 0.69 | CA12 (0.33) | — | |
| SCHEMBL17844175 | 0.68 | CA12 (0.38) | — | |
| SCHEMBL17844244 | 0.67 | MTNR1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |