Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197239 | 0.78 | GSK3B (0.43) | KDM4ESMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL5185824 | 0.75 | NPBWR1 (0.43) | KDM4ESMN1; SMN2HSD17B10MAPTLMNA | |
| SCHEMBL5185609 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2MAPTHTTKMT2AMEN1 | |
| SCHEMBL17844146 | 0.73 | HTR1B (0.39) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL3541635 | 0.71 | MAPT (0.49) | MAPK1KDM4ESMN1; SMN2HSD17B10MAPT | |
| SCHEMBL2001283 | 0.71 | KDM4E (0.37) | MAPK1KDM4ESMN1; SMN2HSD17B10MAPT | |
| SCHEMBL17844238 | 0.69 | SMN1; SMN2 (0.43) | MAPK1KDM4ESMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4973142 | 0.63 | MAPK1 (0.42) | MAPK1KDM4ESMN1; SMN2HSD17B10MAPT | |
| SCHEMBL17844229 | 0.62 | MEN1 (0.48) | MAPK1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL17844241 | 0.62 | MAPK10 (0.42) | MAPK1MAPTHTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |