Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3541635 | 0.91 | MAPT (0.49) | SMN1; SMN2GAAMAPK1L3MBTL1MAPT | |
| SCHEMBL3544822 | 0.84 | TOP2A (0.42) | SMN1; SMN2GAAMAPK1L3MBTL1MAPT | |
| SCHEMBL5197239 | 0.77 | GSK3B (0.43) | SMN1; SMN2GAAMAPTALDH1A1KDM4E | |
| SCHEMBL5184337 | 0.75 | MAOA (0.42) | GAAL3MBTL1ALDH1A1HPGDUSP2 | |
| SCHEMBL1997180 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMAPK1L3MBTL1MAPT | |
| SCHEMBL5185824 | 0.73 | NPBWR1 (0.43) | SMN1; SMN2GAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL17844146 | 0.73 | HTR1B (0.39) | SMN1; SMN2L3MBTL1MAPTLMNAHTR1D | |
| SCHEMBL17844226 | 0.69 | MAPK1 (0.37) | SMN1; SMN2GAAMAPK1MAPTALDH1A1 | |
| SCHEMBL17844229 | 0.64 | MEN1 (0.48) | SMN1; SMN2GAAMAPK1L3MBTL1MAPT | |
| SCHEMBL4094631 | 0.64 | POLB (0.72) | SMN1; SMN2GAAMAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |