Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844212 | 0.90 | MTNR1A (0.42) | DRD2DRD4KDM4EKMT2AMEN1 | |
| SCHEMBL17844232 | 0.90 | DRD2 (0.44) | HRH2HDAC1HDAC2DRD2DRD4 | |
| SCHEMBL17844246 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2HDAC1HDAC2HTR7 | |
| SCHEMBL17844230 | 0.88 | DRD2 (0.46) | HRH2DRD2DRD4KDM4EGPR84 | |
| SCHEMBL5186747 | 0.87 | PTPN2 (0.37) | HDAC1HDAC2DRD2DRD4GPR84 | |
| SCHEMBL17844247 | 0.86 | HTR1B (0.39) | DRD2DRD4KDM4EGPR84KMT2A | |
| SCHEMBL17844178 | 0.83 | DRD4 (0.43) | DRD2DRD4KDM4EGPR84KMT2A | |
| SCHEMBL17844214 | 0.82 | CHRNB2 (0.44) | KDM4E | |
| SCHEMBL5185121 | 0.82 | GPR84 (0.35) | GPR84KMT2AMEN1 | |
| SCHEMBL17844180 | 0.81 | KDM4E (0.37) | KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |