SCHEMBL1784836

SCHEMBL1784836

CCOC(=O)C(C(C(=O)OCC)C(C)C(F)(F)F)C(C)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
POLB P06746 1/20 0.35
MMP8 P22894 1/20 0.34
TRPA1 O75762 1/20 0.33
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
EPHX2 P34913 2/20 0.32
PPARG P37231 2/20 0.32
HPGD P15428 1/20 0.32
PIN1 Q13526 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958017 0.92 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL30791494 0.86 POLB (0.32) POLBMMP8
SCHEMBL16781658 0.83 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL6741832 0.83 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL19690464 0.81 TSHR (0.41) ALDH1A1GAAHTT
SCHEMBL10863109 0.81 HTT (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL18376969 0.81 HTT (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL21360098 0.80 EPHX2 (0.30) ALDH1A1POLBEPHX2PPARG
SCHEMBL3906700 0.79 ALOX15 (0.38) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL15534315 0.79 ALOX15 (0.38) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
CN-108117617-A A kind of ingredient of solid catalyst and catalyst for olefinic polymerization 任丘市利和科技发展有限公司 2018-06-05 CN disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
CN-107417819-A A kind of ingredient of solid catalyst, catalyst and its application for olefinic polymerization 北京利和知信科技有限公司 2017-12-01 CN disclosed
CN-107417818-A It is a kind of for the catalytic component of olefinic polymerization, preparation method and catalyst 北京利和知信科技有限公司 2017-12-01 CN disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
EP-2185600-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE Dow Global Technologies Inc. (US) 2010-05-19 EP disclosed
WO-2009029447-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B ALDH1A1 2055/4885LMNA 2302/4885HSD17B10 1638/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 ALDH1A1 2496/4885LMNA 3701/4885HSD17B10 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.