Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66565 | 0.75 | KDM4E (0.35) | ALDH1A1HSD17B10KDM4EHTTKMT2A | |
| SCHEMBL427634 | 0.70 | TDP1 (0.43) | ALDH1A1HSD17B10TDP1KDM4EKMT2A | |
| SCHEMBL714154 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1KDM4EHTT | |
| SCHEMBL19951537 | 0.70 | NPC1 (0.33) | KDM4E | |
| SCHEMBL8779774 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL4543420 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1KDM4EHTT | |
| SCHEMBL31713455 | 0.67 | LMNA (0.33) | ALDH1A1TDP1HTTKMT2A | |
| SCHEMBL789628 | 0.67 | ALPL (0.47) | ALDH1A1HTTKMT2A | |
| SCHEMBL11048012 | 0.67 | HTR6 (0.50) | ALDH1A1HSD17B10TDP1KDM4EHTT | |
| SCHEMBL1464993 | 0.66 | S1PR1 (0.37) | ALDH1A1HSD17B10HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643299-B1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA SA (ES) | 2016-06-22 | — | — | EP | disclosed |