Sugi Predict

Sugi Predict / Compounds / SCHEMBL714154

SCHEMBL714154

SCHEMBL714154

O=S(=O)(Cl)c1ccc(Br)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ CA2 P00918 3/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA4 P22748 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA7 P43166 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ CA13 Q8N1Q1 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ ADRA2A P08913 2/20 0.34
▸ ADRA2B P18089 2/20 0.34
▸ ADRA2C P18825 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4543420 0.98 ALDH1A1 (0.39) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL21510181 0.82 ALDH1A1 (0.43) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL7772460 0.78 CA2 (0.61) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL4259013 0.78 ALDH1A1 (0.45) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL386709 0.78 ALDH1A1 (0.41) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL31527795 0.77 CA2 (0.59) ALDH1A1KDM4ECA2CA12CA1
Hydrochloric Acid SCHEMBL27819072 0.77 ALDH1A1 (0.44) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL1465207 0.76 NFE2L2 (0.42) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL16180718 0.75 ALDH1A1 (0.38) ALDH1A1KDM4ECA2CA12CA1
SCHEMBL3603004 0.75 GBA1 (0.44) ALDH1A1KDM4ECA2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070902-A1 SULFONYL DERIVATIVES AS CCR6 INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2026-03-12 — — US disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
EP-4702015-A1 CDK2 INHIBITORS AND METHODS OF USING SAME Shenzhen Ionova Life Science Co., Ltd. (CN) 2026-03-04 — — EP disclosed
EP-4630402-A1 SULFONYL DERIVATIVES AS CCR6 INHIBITORS F. Hoffmann-La Roche AG (CH) 2025-10-15 — — EP disclosed
US-20250275959-A1 COMPOUNDS AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. 2025-09-04 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
WO-2025129023-A1 INDOLE AMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2025-06-19 — — WO disclosed
US-20250115576-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2025-04-10 — — US disclosed
US-12209075-B2 Pyridine-sulfonamide derivatives as sodium channel inhibitors GENENTECH, INC. (US) 2025-01-28 — — US disclosed
WO-2024222678-A1 CDK2 INHIBITORS AND METHODS OF USING SAME SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) 2024-10-31 — — WO disclosed
EP-1778679-A1 PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS GLAXO GROUP LIMITED (GB) 2007-05-02 — — EP disclosed
WO-2007039581-A1 IMIDAZOLYL-SUBSTITUTED DIAZABENZOPHENONE COMPOUNDS NYCOMED GMBH (DE) 2007-04-12 — — WO disclosed
WO-2007039580-A1 IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS NYCOMED GMBH (DE) 2007-04-12 — — WO disclosed
WO-2007039578-A1 IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS NYCOMED GMBH (DE) 2007-04-12 — — WO disclosed
WO-2006134481-A1 INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 PFIZER INC. (US) 2006-12-21 — — WO disclosed
WO-2006113261-A2 INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I BRISTOL-MYERS SQUIBB COMPANY (US) 2006-10-26 — — WO disclosed
US-20060235028-A1 Inhibitors of 11-beta hydroxysteroid dehydrogenase type I BRISTOL-MYERS SQUIBB COMPANY 2006-10-19 — — US disclosed
EP-1667993-A1 HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM Abbott GmbH & Co. KG (DE) 2006-06-14 — — EP disclosed
WO-2006010629-A1 PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS GLAXO GROUP LIMITED (GB) 2006-02-02 — — WO disclosed
WO-2005030755-A1 HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM ABBOTT GMBH & CO. KG (DE) 2005-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235028-A1 Inhibitors of 11-beta hydroxysteroid dehydrogenase type I HSD11B1, HSD3B1, HSD17B1 ALDH1A1 92/4885KDM4E 3845/4885CA2 3980/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B ALDH1A1 1864/4885KDM4E 800/4885CA2 199/4885
US-20260070902-A1 SULFONYL DERIVATIVES AS CCR6 INHIBITORS CCR6, CCR1, CCR4 ALDH1A1 2086/4885KDM4E 2904/4885CA2 614/4885
US-12209075-B2 Pyridine-sulfonamide derivatives as sodium channel inhibitors SCN1B, CACNA1A, SCN1A ALDH1A1 3192/4885KDM4E 1990/4885CA2 147/4885
US-20250275959-A1 COMPOUNDS AND METHODS OF THEIR USE ACSL5, ACSL3, ACSL6 ALDH1A1 1002/4885KDM4E 3659/4885CA2 958/4885
US-20250115576-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF F12, REN, ZYX ALDH1A1 2171/4885KDM4E 3360/4885CA2 203/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 ALDH1A1 982/4885KDM4E 4009/4885CA2 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.