Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PRKDC | P78527 | 4/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177374 | 0.91 | ALOX5 (0.57) | ALOX5PRKDCPIK3CDPIK3CBHDAC8 | |
| SCHEMBL12108 | 0.91 | ALOX5 (0.46) | ALOX5TTRMCL1MEN1KMT2A | |
| SCHEMBL16477678 | 0.89 | ALOX5 (0.55) | ALOX5PRKDCPIK3CDPIK3CBHDAC8 | |
| SCHEMBL15785766 | 0.89 | PGR (0.44) | ALOX5TTRMCL1MEN1KMT2A | |
| SCHEMBL19521824 | 0.89 | ALOX5 (0.58) | ALOX5PRKDCTTRGGPS1ATM | |
| SCHEMBL5028273 | 0.89 | ALOX5 (0.66) | ALOX5PRKDCPIK3CDPIK3CBHDAC8 | |
| SCHEMBL12799811 | 0.89 | MCL1 (0.47) | ALOX5PRKDCMCL1MAOAALDH1A1 | |
| SCHEMBL18179417 | 0.88 | ALOX5 (0.51) | ALOX5PRKDCPIK3CDPIK3CBHDAC8 | |
| SCHEMBL16185335 | 0.87 | NPC1 (0.44) | ALOX5PRKDCMCL1RXFP1MAOA | |
| SCHEMBL10945864 | 0.87 | ALOX5 (0.68) | ALOX5PRKDCPIK3CDPIK3CBHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2019-10-01 | — | — | US | disclosed |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | UDC IRELAND LTD (IE) | 2019-09-05 | — | — | US | disclosed |
| US-9806270-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2017-10-31 | — | — | US | disclosed |
| EP-3034508-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2016-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | EIF4A1, ITPR2, ITPR1 | ALOX5 4573/4885PRKDC 2909/4885PIK3CD 318/4885 |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | PAH, NISCH, KCNH1 | ALOX5 4765/4885PRKDC 3618/4885PIK3CD 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.