SCHEMBL1785391

SCHEMBL1785391

CC(C)(C)[Si](C)(C)OCCCCN

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.38
ODC1 P11926 1/20 0.35
NFKB1 P19838 1/20 0.32
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30
CA5B Q9Y2D0 2/20 0.30
DNM1 Q05193 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8057981 0.98 DUT (0.37) DUTODC1CA12CA1CA2
Hydrochloric Acid SCHEMBL29281207 0.98 DUT (0.37) DUTODC1NFKB1DNM1
SCHEMBL28903381 0.98 DUT (0.37) DUTODC1CA12CA1CA2
SCHEMBL100630 0.98 DUT (0.37) DUTODC1CA12CA1CA2
SCHEMBL8156589 0.98 DUT (0.37) DUTODC1CA12CA1CA2
SCHEMBL1038400 0.93 ODC1 (0.42) DUTODC1
SCHEMBL8063404 0.88 DUT (0.43) DUT
SCHEMBL14245094 0.85 DUT (0.42) DUT
SCHEMBL9007756 0.85 DUT (0.42) DUT
SCHEMBL27241092 0.85 DUT (0.42) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026047069-A1 SYNTHESIS AND USE OF NOVEL DRIMANE SESQUITERPENOIDS OF KHAMKHAINE TYPE FROM THAI BASIDIOMYCOTA OTTO-VON-GUERICKE-UNIVERSITÄT MAGDEBURG KÖRPERSCHAFT DES ÖFFENTLICHEN RECHTS (DE) 2026-03-05 WO disclosed
EP-4698517-A1 <SUP2/>? <SUB2/>?4?NOVEL COMPOUNDS AS ?? <NS1:SUB>7</NS1:SUB>?INHIBITORS Evotec International GmbH (DE) 2026-02-25 EP disclosed
US-20250340556-A1 PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF SOLTEGO INC (US) 2025-11-06 US disclosed
EP-4526307-A1 PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF Soltego, Inc. (US) 2025-03-26 EP disclosed
WO-2024218058-A1 NOVEL COMPOUNDS AS α4β7 INHIBITORS EVOTEC INTERNATIONAL GMBH (DE) 2024-10-24 WO disclosed
EP-4396160-A1 STEREOCHEMICALLY PURE LIPIDS FOR NUCLEIC ACID DELIVERY Studiengesellschaft Kohle gGmbH (DE) 2024-07-10 EP disclosed
CN-117881654-A Stereochemically pure lipids for nucleic acid delivery 科勒研究非盈利有限责任公司 2024-04-12 CN disclosed
WO-2023225097-A1 PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF SOLTEGO, INC. (US) 2023-11-23 WO disclosed
WO-2023031210-A1 STEREOCHEMICALLY PURE LIPIDS FOR NUCLEIC ACID DELIVERY STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-03-09 WO disclosed
US-11369586-B2 Antifungal peptoids Middle Tennessee State University (US) 2022-06-28 US disclosed
US-20130123231-A1 ACC INHIBITORS AND USES THEREOF Nimbus Apollo, Inc. (US) 2013-05-16 US disclosed
US-20110124630-A1 STEMONAMIDE SYNTHESIS INTERMEDIATE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF CANCER NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2011-05-26 US disclosed
EP-2322528-A1 STEMONAMIDE SYNTHESIS INTERMEDIATE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF CANCER National University Corporation Kanazawa University (JP) 2011-05-18 EP disclosed
US-20100298392-A1 Isoindoline Derivatives For The Treatment Of Arrhythmias ASTRAZENECA AB (SE) 2010-11-25 US disclosed
EP-2049484-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS AstraZeneca AB (SE) 2009-04-22 EP disclosed
WO-2008008022-A1 ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS ASTRAZENECA AB (SE) 2008-01-17 WO disclosed
US-20080015237-A1 NEW COMPOUNDS I/418 ASTRAZENECA AB (SE) 2008-01-17 US disclosed
US-6953785-B2 Estra-1,3,5(10)-triene derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 2005-10-11 US disclosed
US-20030216362-A1 Estra-1,3,5 (10)-triene derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-11-20 US disclosed
EP-1284272-A1 ESTRA-1,3,5(10)-TRIENE DERIVATIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340556-A1 PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF SIK2, SIK1, SIK3 DUT 899/4885ODC1 1318/4885NFKB1 1722/4885
US-20030216362-A1 Estra-1,3,5 (10)-triene derivatives STS, SULT1E1, SULT1A1 DUT 1178/4885ODC1 2388/4885NFKB1 3039/4885
US-11369586-B2 Antifungal peptoids ERG28, DPM1, QPCTL DUT 1823/4885ODC1 2020/4885NFKB1 4170/4885
US-20110124630-A1 STEMONAMIDE SYNTHESIS INTERMEDIATE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF CANCER SULT1E1, CCNE1, SULT1A1 DUT 206/4885ODC1 1077/4885NFKB1 2214/4885
US-20080015237-A1 NEW COMPOUNDS I/418 KCNH1, KCNH2, KCNH3 DUT 2853/4885ODC1 1293/4885NFKB1 3001/4885
US-20130123231-A1 ACC INHIBITORS AND USES THEREOF ACACA, ACACB, ACAT2 DUT 619/4885ODC1 465/4885NFKB1 3263/4885
US-20100298392-A1 Isoindoline Derivatives For The Treatment Of Arrhythmias KCNH1, KCNH2, KCNQ2 DUT 1596/4885ODC1 2120/4885NFKB1 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.