Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336950 | 0.88 | TDP1 (0.47) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL32659715 | 0.87 | PDGFRB (0.51) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL2247382 | 0.86 | PDGFRB (0.50) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL1786813 | 0.86 | MEN1 (0.51) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL2903296 | 0.86 | TDP1 (0.53) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL24152418 | 0.84 | CRHBP (0.44) | MEN1KMT2AGUSBNPC1RAB9A | |
| SCHEMBL3064007 | 0.84 | LMNA (0.53) | KMT2AGUSBNPC1GAAPOLB | |
| SCHEMBL10381873 | 0.84 | POLB (0.42) | MEN1KMT2ATDP1GUSBNPC1 | |
| SCHEMBL31575920 | 0.83 | PDGFRB (0.48) | MEN1KMT2ATDP1PDGFRBFGFR1 | |
| SCHEMBL1788077 | 0.83 | PDGFRB (0.55) | MEN1KMT2ATDP1PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390577-A | Continuous preparation process of 2-chloro-4-fluoro-5-nitrobenzoic acid methyl ester | 苏利(宁夏)新材料科技有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-117486818-A | N-phenyl thiotriazinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | claimed |
| EP-4225739-B1 | PREPARATION OF BENZIMIDAZOLONE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4081521-B1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LTD (IN) | 2025-12-10 | — | — | EP | disclosed |
| EP-4567029-A1 | METHOD FOR PREPARING URACIL COMPOUND CONTAINING CARBOXYLATE FRAGMENT | Jiangsu Flag Chemical Industry Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179030-A1 | METHOD FOR PREPARING A URACIL COMPOUND CONTAINING A CARBOXYLATE FRAGMENT | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| CN-119613399-A | Tetra-substituted benzoate compound containing alkoxy acetate substituent and application thereof | 江西天宇化工有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119390577-A | Continuous preparation process of 2-chloro-4-fluoro-5-nitrobenzoic acid methyl ester | 苏利(宁夏)新材料科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119390577-A | Continuous preparation process of 2-chloro-4-fluoro-5-nitrobenzoic acid methyl ester | 苏利(宁夏)新材料科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| US-20240366608-A1 | PHARMACEUTICAL COMBINATIONS OF SOS1 INHIBITORS FOR TREATING AND/OR PREVENTING CANCER | LUPIN LIMITED (IN) | 2024-11-07 | — | — | US | disclosed |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-20130203730-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2013-08-08 | — | — | US | disclosed |
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |
| US-20120115845-A1 | THERAPEUTIC AGENTS | ALLEN JACK MCQUEEN (GB) | 2012-05-10 | — | — | US | disclosed |
| US-20110124621-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2011-05-26 | — | — | US | disclosed |
| CN-101883762-A | Benzothiazoles as modulators of growth hormone releasing hormone receptors | ASTRAZENECA AB | 2010-11-10 | — | — | CN | disclosed |
| EP-2205576-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2010-07-14 | — | — | EP | disclosed |
| US-20090186870-A1 | Therapeutic Agents - 802 | ASTRAZENECA AB (SE) | 2009-07-23 | — | — | US | disclosed |
| WO-2009047558-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | WO | disclosed |
| US-4670046-A | Tetrahydrophthalimide compounds, as post-emergence herbicides for use in soybean fields | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203730-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | GPR119, GHSR, GLP1R | MEN1 2250/4885KMT2A 1721/4885TDP1 4366/4885 |
| US-20240366608-A1 | PHARMACEUTICAL COMBINATIONS OF SOS1 INHIBITORS FOR TREATING AND/OR PREVENTING CANCER | NRAS, KRAS, PRMT1 | MEN1 625/4885KMT2A 157/4885TDP1 425/4885 |
| US-20120115845-A1 | THERAPEUTIC AGENTS | GPR119, MC2R, MC4R | MEN1 692/4885KMT2A 3139/4885TDP1 4230/4885 |
| US-20250179030-A1 | METHOD FOR PREPARING A URACIL COMPOUND CONTAINING A CARBOXYLATE FRAGMENT | UNG, DPYD, DDT | MEN1 4506/4885KMT2A 1233/4885TDP1 362/4885 |
| US-20090186870-A1 | Therapeutic Agents - 802 | GPR119, SLC5A2, MC2R | MEN1 1253/4885KMT2A 2304/4885TDP1 4334/4885 |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | BICRA, BRD4, CNR1 | MEN1 928/4885KMT2A 92/4885TDP1 2609/4885 |
| US-20110124621-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | GPR119, GHSR, GLP1R | MEN1 2250/4885KMT2A 1721/4885TDP1 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.