SCHEMBL17864890

SCHEMBL17864890

O=C(NCc1cccc(CNC(=O)OCCOc2ccccc2)c1)OCCOc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
RECQL P46063 1/20 0.56
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
HPGD P15428 1/20 0.51
PADI3 Q9ULW8 1/20 0.50
PADI4 Q9UM07 1/20 0.50
TAAR1 Q96RJ0 1/20 0.49
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
THRB P10828 1/20 0.48
MAPT P10636 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ERCC1 P07992 1/20 0.47
ERCC4 Q92889 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346749 0.96 TSHR (0.54) TSHRNPC1RAB9ASMN1; SMN2RECQL
SCHEMBL17552044 0.90 TSHR (0.48) TSHRNPC1RAB9ASMN1; SMN2RECQL
SCHEMBL17346754 0.89 LMNA (0.56) TSHRSMN1; SMN2KMT2AMEN1PADI3
SCHEMBL17864889 0.86 MGLL (0.57) NPC1RAB9ASMN1; SMN2RECQLPADI3
SCHEMBL13625200 0.84 NPC1 (0.61) NPC1RAB9ASMN1; SMN2RECQLPADI3
SCHEMBL17346792 0.84 TSHR (0.53) TSHRSMN1; SMN2KMT2AMEN1PADI3
SCHEMBL17346617 0.83 RAB9A (0.43) TSHRNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL17342588 0.83 PADI3 (0.53) TSHRNPC1RAB9ASMN1; SMN2RECQL
SCHEMBL17346622 0.82 TDP1 (0.51) TSHRNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL17342584 0.80 HDAC3 (0.52) NPC1RAB9ASMN1; SMN2RECQLPADI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 TSHR 1636/4885NPC1 2545/4885RAB9A 1264/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 TSHR 1685/4885NPC1 2604/4885RAB9A 1276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.