SCHEMBL1786706

SCHEMBL1786706

O=Cc1c(F)ccc(B(O)O)c1F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
ERN1 O75460 3/20 0.38
CYP2D6 P10635 1/20 0.36
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895193 1.00 CYP2C9 (0.41) CYP2C9CYP3A4CYP2C19ERN1CYP2D6
SCHEMBL31026008 0.84 ERN1 (0.38) CYP2C9CYP3A4CYP2C19ERN1KDM4E
SCHEMBL26113596 0.81 ALDH1A1 (0.42) KDM4E
SCHEMBL30978619 0.78 CTSL (0.36) CYP2C9CYP3A4CYP2C19ERN1CYP2D6
SCHEMBL3973764 0.76 ERN1 (0.47) ERN1
SCHEMBL31396936 0.76 ERN1 (0.47) ERN1
SCHEMBL31685229 0.75 CYP2C9 (0.46) CYP2C9CYP3A4CYP2C19ERN1CYP2D6
SCHEMBL415893 0.75 CYP2C9 (0.46) CYP2C9CYP3A4CYP2C19ERN1CYP2D6
SCHEMBL29370127 0.75 ERN1 (0.36) ERN1KDM4E
SCHEMBL1786787 0.75 ERN1 (0.36) ERN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115259168-B Cell imprinting polymer with boric acid directional modification and PEG local post-modification, preparation method and application thereof 天津医科大学 2024-07-09 CN claimed
CN-115254047-B Molecularly imprinted and coated polymer, preparation method and application thereof 南京大学 2024-01-02 CN claimed
CN-112098639-B Synthesis and application of secondary antibody with graphene oxide as carrier 天津医科大学 2024-01-02 CN claimed
CN-113512417-B Synthesis and application of fluorescent signal amplifier with graphene oxide as carrier 天津医科大学 2023-09-05 CN claimed
CN-111579467-B Bifunctional graphene oxide composite material and application thereof in detecting adherent cells 天津医科大学 2023-03-14 CN claimed
CN-115254047-A Molecular imprinting and coating polymer, preparation method and application thereof 南京大学 2022-11-01 CN claimed
CN-115259168-A Cell imprinting polymer with boric acid directional modification and PEG local post-modification, preparation method and application thereof 天津医科大学 2022-11-01 CN claimed
CN-113512417-A Synthesis and application of fluorescent signal amplifier with graphene oxide as carrier 天津医科大学 2021-10-19 CN claimed
CN-108722369-B Universal convenient epitope imprinting method and application of obtained molecularly imprinted polymer 南京大学 2020-12-25 CN claimed
CN-112098639-A Synthesis and application of secondary antibody taking graphene oxide as carrier 天津医科大学 2020-12-18 CN claimed
CN-111579467-A Bifunctional graphene oxide composite material and application thereof in detecting adherent cells 天津医科大学 2020-08-25 CN claimed
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
US-12565490-B2 Inhibitors of Receptor Interacting Protein Kinase I for the treatment of disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-03 US disclosed
US-20250128188-A1 BORONIC ACID CONTAINING AFFINITY MEMBRANES DONALDSON COMPANY, INC. 2025-04-24 US disclosed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP disclosed
EP-2050749-A1 PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2009-04-22 EP disclosed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy GFER, MUC1, CTH CYP2C9 2712/4885CYP3A4 2838/4885CYP2C19 2573/4885
US-12565490-B2 Inhibitors of Receptor Interacting Protein Kinase I for the treatment of disease RIPK1, RIPK4, RIPK2 CYP2C9 4207/4885CYP3A4 4165/4885CYP2C19 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.