SCHEMBL1787038

SCHEMBL1787038

CC(c1cnc(C(F)(F)F)s1)S(C)(=O)=NC#N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17804549 0.86 PDE9A (0.30) PDE9A
SCHEMBL7602156 0.81 HCAR2 (0.30)
SCHEMBL3047879 0.74 HDAC6 (0.30)
SCHEMBL305535 0.72 CDK2 (0.34)
SCHEMBL1997902 0.72
SCHEMBL17502564 0.71 PDE9A (0.34) PDE9A
Sulfoxaflor SCHEMBL520711 0.71 LGMN (0.37) PDE9A
Sulfoxaflor SCHEMBL18103859 0.71 LGMN (0.37) PDE9A
Sulfoxaflor SCHEMBL14148160 0.71 LGMN (0.37) PDE9A
Sulfoxaflor SCHEMBL18103858 0.71 LGMN (0.37) PDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223602-A1 Method for improved utilisation of the production potential of genetically modified plants Bayer CropScience AG (DE) 2010-09-01 EP claimed
EP-2323488-B1 METHOD FOR IMPROVING PLANT GROWTH BAYER IP GMBH (DE) 2018-04-18 EP disclosed
US-9763451-B2 Method for improved use of the production potential of genetically modified plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-19 US disclosed
US-9763451-B2 Method for improved use of the production potential of genetically modified plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-19 US disclosed
US-20160044921-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2016-02-18 US disclosed
US-20160044921-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2016-02-18 US disclosed
US-20140287915-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-09-25 US disclosed
US-20140287915-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-09-25 US disclosed
US-8796175-B2 Method for enhancing plant intrinsic defense BAYER CROPSCIENCE AG (DE) 2014-08-05 US disclosed
EP-2338885-B1 Insecticidal N-Substituted (2-Substituted-1,3-Thiazol) Alkyl Sulfoximines DOW AGROSCIENCES LLC (US) 2012-10-31 EP disclosed
WO-2010075966-A1 METHOD FOR IMPROVED USE OF THE PRODUCTION POTENTIAL OF GENETICALLY MODIFIED PLANTS BAYER CROPSCIENCE AG (DE) 2010-07-08 WO disclosed
WO-2010022897-A2 METHOD FOR IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-03-04 WO disclosed
WO-2010022897-A2 METHOD FOR IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-03-04 WO disclosed
WO-2009135613-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-11-12 WO disclosed
EP-2057135-A1 INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES Dow AgroSciences LLC (US) 2009-05-13 EP disclosed
WO-2008027539-A1 INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2008-03-06 WO disclosed
WO-2008027539-A1 INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2008-03-06 WO disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160044921-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS ACHE, ACAT2, ACAT1 PDE9A 512/4885
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines TST, NIT2, MSL1 PDE9A 3377/4885
US-20140287915-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS ACHE, ACAT2, ACAT1 PDE9A 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.