Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | HPGD | P15428 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.81 |
| ▸ | RGS17 | Q9UGC6 | 1/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irigenol SCHEMBL2465996 | 0.90 | MAPT (1.00) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL16432690 | 0.81 | ALOX15 (0.78) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL13279932 | 0.79 | MAPT (0.75) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL737653 | 0.79 | ALDH1A1 (0.75) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL30525493 | 0.79 | MAPT (0.75) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL3385694 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL28740045 | 0.78 | PTPN1 (0.70) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL6349946 | 0.77 | MEN1 (0.58) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL29931737 | 0.77 | ABCB1 (0.75) | ALDH1A1CYP3A4MAPTHPGDMEN1 | |
| SCHEMBL18326541 | 0.73 | EGFR (0.60) | ALDH1A1CYP3A4MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185843-A1 | TREATING ALCOHOL-MEDIATED DISORDERS BY INHIBITION OF RGS6 | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185843-A1 | TREATING ALCOHOL-MEDIATED DISORDERS BY INHIBITION OF RGS6 | RGS4, RGS16, ADH1A | ALDH1A1 252/4885CYP3A4 2324/4885MAPT 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.