Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17900564 | 0.94 | TAS1R3 (0.35) | TAS1R3TAS1R1ALDH1A1MAPTKMT2A | |
| SCHEMBL17900631 | 0.85 | RORC (0.43) | TAS1R3TAS1R1MEN1ALDH1A1MAPT | |
| SCHEMBL17900781 | 0.85 | LPAR1 (0.40) | MEN1KMT2AL3MBTL1LPAR1 | |
| SCHEMBL17900665 | 0.85 | TAS1R3 (0.40) | TAS1R3TAS1R1MEN1HPGDKMT2A | |
| SCHEMBL17900776 | 0.81 | CTSA (0.38) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17900563 | 0.81 | TAS1R3 (0.35) | TAS1R3TAS1R1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL17900711 | 0.81 | ALDH1A1 (0.42) | TAS1R3TAS1R1MEN1ALDH1A1MAPT | |
| SCHEMBL17902237 | 0.80 | LPAR1 (0.40) | TAS1R3TAS1R1ACHELPAR1 | |
| SCHEMBL20348365 | 0.78 | LPAR1 (0.38) | ACHELPAR1 | |
| SCHEMBL17905560 | 0.78 | RORC (0.35) | TAS1R3TAS1R1MEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| WO-2016109305-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109304-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | TAS1R3 1246/4885TAS1R1 1444/4885CRHR1 3123/4885 |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | PFAS, CYP1A2, CYP4F12 | TAS1R3 1121/4885TAS1R1 1325/4885CRHR1 2685/4885 |
| US-10173981-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | TAS1R3 1246/4885TAS1R1 1444/4885CRHR1 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.