Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17900665 | 0.93 | TAS1R3 (0.40) | TAS1R3TAS1R1RORCNPSR1MRGPRX4 | |
| SCHEMBL17900631 | 0.89 | RORC (0.43) | TAS1R3TAS1R1ALDH1A1PKMRORC | |
| SCHEMBL17900564 | 0.84 | TAS1R3 (0.35) | TAS1R3TAS1R1ALDH1A1PKM | |
| SCHEMBL17900673 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CARM1PRMT6NPSR1TDP1 | |
| SCHEMBL17900548 | 0.81 | MEN1 (0.39) | TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL17900560 | 0.81 | TAS1R3 (0.38) | TAS1R3TAS1R1ALDH1A1NPSR1CYP2C9 | |
| SCHEMBL17900769 | 0.78 | PPARA (0.48) | ALDH1A1PKMRORCCYP1A2CYP3A4 | |
| SCHEMBL17900663 | 0.78 | PPARA (0.48) | ALDH1A1PKMRORCCYP1A2CYP3A4 | |
| SCHEMBL17900630 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1CYP3A4TDP1 | |
| SCHEMBL17900662 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| WO-2016109305-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109304-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | TAS1R3 1246/4885TAS1R1 1444/4885ALDH1A1 1130/4885 |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | PFAS, CYP1A2, CYP4F12 | TAS1R3 1121/4885TAS1R1 1325/4885ALDH1A1 1067/4885 |
| US-10173981-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | TAS1R3 1246/4885TAS1R1 1444/4885ALDH1A1 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.