SCHEMBL1791983

SCHEMBL1791983

CC(C)(C)c1ccc(C(C)(C)C)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.32
HMBS P08397 1/20 0.32
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19221617 0.84 ALDH1A1 (0.31) DAOALDH1A1HPGD
SCHEMBL12071844 0.82 NPC1 (0.31) MAPT
SCHEMBL21718510 0.80
SCHEMBL2756557 0.76 BCHE (0.32) BCHEACHEGABRA1GABRB2
SCHEMBL10262151 0.76 ALDH1A1 (0.32) ALDH1A1HPGD
SCHEMBL14791094 0.74
SCHEMBL7616986 0.74 HIF1A (0.39) DAOALDH1A1MAPT
SCHEMBL15043728 0.74 DAO (0.39) DAOALDH1A1HPGDTSHRLMNA
SCHEMBL15829387 0.74 LOXL2 (0.33)
SCHEMBL11365710 0.69 MEN1 (0.38) DAOALDH1A1HPGDTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754694-A Method for synthesizing Reidesvir by asymmetric catalysis of non-protecting group nucleoside 上海交通大学 2021-12-07 CN claimed
EP-4737461-A1 NOVEL COMPOUND, PRECURSOR COMPOSITION COMPRISING SAME, AND METHOD FOR MANUFACTURING THIN FILM USING SAME Hansol Chemical Co., Ltd (KR) 2026-05-06 EP disclosed
WO-2025005677-A1 NOVEL COMPOUND, PRECURSOR COMPOSITION COMPRISING SAME, AND METHOD FOR MANUFACTURING THIN FILM USING SAME 주식회사 한솔케미칼 2025-01-02 WO disclosed
CN-115246759-B Method for preparing hexene and co-producing octene and decene by oligomerization 中国石油天然气股份有限公司 2024-10-29 CN disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12024528-B2 Bridged tricyclic carbamoylpyridone compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-02 US disclosed
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders ARDELYX, INC. (US) 2024-06-25 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20230339971-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-10-26 US disclosed
US-20080027377-A1 Catheters having actuatable lumen assemblies BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-01-31 US disclosed
US-20080012010-A1 ORGANIC ELECTRONIC DEVICE, METHOD FOR PRODUCTION THEREOF, AND ORGANIC SEMICONDUCTOR MOLECULE SONY CORPORATION (JP) 2008-01-17 US disclosed
US-20070185093-A1 Benzotriazepine derivatives and their use as gastrin and cholecystokinin receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 2007-08-09 US disclosed
US-20070082892-A1 Benzotriazepine derivatives and their use as gastrin and cholecystokinin receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 2007-04-12 US disclosed
US-20070066819-A1 PROCESS FOR THE PREPARATION OF BENZOTRIAZEPINE DERIVATIVES JANSSEN PHARMACUETICA N.V., (BE) 2007-03-22 US disclosed
CN-1142192-C Catalyst system containing reaction product of liquid cilicone and polyamine 伊奎斯塔化学有限公司 2004-03-17 CN disclosed
EP-0741145-B1 Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL CO (JP) 1999-12-29 EP disclosed
CN-1220671-A Catalyst system comprising the reaction product of a liquid silicone and a polyamine EQUISTA CHEMICAL CO LTD (US) 1999-06-23 CN disclosed
CN-1145370-A Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL CO (JP) 1997-03-19 CN disclosed
EP-0741145-A1 Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066819-A1 PROCESS FOR THE PREPARATION OF BENZOTRIAZEPINE DERIVATIVES CCKBR, CCKAR, GRPR DAO 1373/4885ALDH1A1 3751/4885HPGD 2087/4885
US-20230339971-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF SDHA, SDHB, DHFR DAO 1528/4885ALDH1A1 840/4885HPGD 291/4885
US-20070082892-A1 Benzotriazepine derivatives and their use as gastrin and cholecystokinin receptor ligands CCKBR, GRPR, CCKAR DAO 1450/4885ALDH1A1 2440/4885HPGD 866/4885
US-12043613-B2 Inhibitors of SARM1 SARM1, SMN1; SMN2, SARNP DAO 4084/4885ALDH1A1 4157/4885HPGD 4393/4885
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 DAO 1630/4885ALDH1A1 1427/4885HPGD 3064/4885
US-20070185093-A1 Benzotriazepine derivatives and their use as gastrin and cholecystokinin receptor ligands CCKBR, GRPR, CCKAR DAO 1450/4885ALDH1A1 2440/4885HPGD 866/4885
US-12024528-B2 Bridged tricyclic carbamoylpyridone compounds and uses thereof SDHA, SDHB, DPYD DAO 1443/4885ALDH1A1 684/4885HPGD 264/4885
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders SLC10A1, SLC10A2, FABP3 DAO 3538/4885ALDH1A1 2512/4885HPGD 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.