SCHEMBL17933755

SCHEMBL17933755

CN1c2ccccc2CSc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.57
▸ HSD17B3 P37058 5/20 0.54
▸ ADRA2A P08913 3/20 0.44
▸ ADRA2B P18089 3/20 0.44
▸ ADRA2C P18825 3/20 0.44
▸ HTR2C P28335 3/20 0.44
▸ HTR2B P41595 3/20 0.44
▸ DRD3 P35462 2/20 0.44
▸ HTR2A P28223 2/20 0.44
▸ ADRA1A P35348 2/20 0.44
▸ HRH1 P35367 2/20 0.44
▸ HTR1A P08908 1/20 0.44
▸ CHRM5 P08912 1/20 0.44
▸ DRD2 P14416 1/20 0.44
▸ DRD1 P21728 1/20 0.44
▸ DRD4 P21917 1/20 0.44
▸ DRD5 P21918 1/20 0.44
▸ HRH2 P25021 1/20 0.44
▸ ADRA1D P25100 1/20 0.44
▸ HTR1D P28221 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21311762 0.78 HSD17B3 (0.49) HSD17B3ADRA2AADRA2BADRA2CHTR2C
SCHEMBL8140807 0.78 LMNA (0.57) MAOAHSD17B3MEN1KMT2AMAPT
SCHEMBL12269612 0.76 ACHE (0.44) MAOAHSD17B3ADRA2AADRA2BADRA2C
SCHEMBL2604390 0.73 MAOA (0.52) MAOAHSD17B3ADRA2AADRA2BADRA2C
SCHEMBL29351597 0.73 MAOA (0.52) MAOAADRA2AADRA2BADRA2CHTR2C
SCHEMBL975897 0.73 MAOA (0.52) MAOAADRA2AADRA2BADRA2CHTR2C
SCHEMBL231247 0.73 MAOA (1.00) MAOAADRA2AADRA2BADRA2CHTR2C
SCHEMBL29377505 0.73 MAOA (1.00) MAOAADRA2AADRA2BADRA2CHTR2C
SCHEMBL23188979 0.73 MAOA (0.44) MAOAHSD17B3MEN1KMT2AALDH1A1
SCHEMBL14387598 0.73 MAOA (0.44) MAOAHSD17B3TDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11186669-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2021-11-30 — — US disclosed
US-20210284766-A1 RETARDATION FILM, ELLIPTICALLY POLARIZING PLATE, AND DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2021-09-16 — — US disclosed
US-11046889-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-06-29 — — US disclosed
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same DIC CORPORATION (JP) 2021-02-23 — — US disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 — — US disclosed
US-10723952-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-07-28 — — US disclosed
US-10649124-B2 Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film DIC CORPORATION (JP) 2020-05-12 — — US disclosed
US-10479844-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2019-11-19 — — US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 — — US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 — — US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 — — WO disclosed
WO-2017038265-A1 POWDER MIXTURE DIC株式会社 2017-03-09 — — WO disclosed
WO-2016114346-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2016-07-21 — — WO disclosed
WO-2016114252-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2016-07-21 — — WO disclosed
WO-2016114347-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2016-07-21 — — WO disclosed
WO-2016114253-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2016-07-21 — — WO disclosed
WO-2016114348-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL DIC株式会社 2016-07-21 — — WO disclosed
WO-2016114254-A1 RETARDATION PLATE AND CIRCULARLY POLARIZING PLATE DIC株式会社 2016-07-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same CRYAA, IK, LCP1 MAOA 3866/4885HSD17B3 4449/4885ADRA2A 3190/4885
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 MAOA 2155/4885HSD17B3 2522/4885ADRA2A 4209/4885
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY SMC4, PHOSPHO1, SMCHD1 MAOA 1780/4885HSD17B3 2602/4885ADRA2A 4665/4885
US-11046889-B2 Polymerizable compound and optically anisotropic body OCIAD1, RCC1, OCIAD2 MAOA 543/4885HSD17B3 2020/4885ADRA2A 3770/4885
US-10723952-B2 Polymerizable compound and optically anisotropic body SMC4, SMCHD1, PHOSPHO1 MAOA 1697/4885HSD17B3 2605/4885ADRA2A 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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