Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | XBP1 | P17861 | 2/20 | 0.75 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390429 | 0.86 | ALDH1A1 (1.00) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17969765 | 0.85 | MEN1 (0.79) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17969764 | 0.82 | LMNA (0.73) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17969757 | 0.81 | MEN1 (0.71) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL30885094 | 0.81 | LMNA (0.88) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL8147516 | 0.80 | LMNA (0.75) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL21470360 | 0.79 | MEN1 (0.79) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17969761 | 0.77 | LMNA (0.66) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9319418 | 0.76 | MAPT (0.60) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7099261 | 0.76 | LMNA (0.73) | MEN1LMNAKMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764886-B1 | Electrophotosensitive material containing a naphthoquinone derivative | KYOCERA MITA CORP (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-5994012-A | CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER | MITA INDUSTRIAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5863688-A | REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE | MITA INDUSTRIAL CO., LTD (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0764886-A2 | Naphthoquinone derivative and electrophotosensitive material using the same | MITA INDUSTRIAL CO. LTD. (JP) | 1997-03-26 | — | — | EP | disclosed |