Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.59 |
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | VHL | P40337 | 1/20 | 0.49 |
| ▸ | ELOC | Q15369 | 1/20 | 0.49 |
| ▸ | ELOB | Q15370 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673182 | 1.00 | MAOA (0.59) | MAOAMAOBCYP2A6F7PARP1 | |
| SCHEMBL7983259 | 0.96 | MAOA (0.59) | MAOAMAOBCYP2A6F7PARP1 | |
| SCHEMBL29506179 | 0.88 | PBRM1 (0.59) | MAOAMAOBF7PARP1F3 | |
| SCHEMBL1151032 | 0.88 | PBRM1 (0.59) | MAOAMAOBF7PARP1F3 | |
| SCHEMBL1798900 | 0.84 | MAOA (0.67) | MAOAMAOBCYP2A6PRKCIVHL | |
| SCHEMBL17011806 | 0.83 | MAOA (0.56) | MAOAMAOBCYP2A6PRKCIVHL | |
| SCHEMBL27844098 | 0.80 | MAOA (0.49) | MAOAMAOBCYP2A6PRKCIVHL | |
| SCHEMBL27843801 | 0.80 | MAOA (0.49) | MAOAMAOBCYP2A6PRKCIVHL | |
| SCHEMBL5108894 | 0.80 | MAOA (0.61) | MAOAMAOBCYP2A6PRKCIVHL | |
| SCHEMBL5543621 | 0.78 | MAOA (0.55) | MAOAMAOBCYP2A6PRKCIMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108928-B | Nitrogen mustard-tetralone derivative, preparation method and application thereof | 广东海洋大学 | 2024-06-11 | — | — | CN | claimed |
| CN-106381324-A | Preparation method of R-7-chloro-1-tetralinylamine | 王际菊 | 2017-02-08 | — | — | CN | claimed |
| US-12637414-B2 | Arylamides and methods of use thereof | GENZYME CORPORATION (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630498-B2 | Arylamides and methods of use thereof | GENZYME CORPORATION (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260055083-A1 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20240270758-A1 | PYRIDINO-OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | ZHEJIANG GENFLEET THERAPEUTICS CO., LTD. (CN) | 2024-08-15 | — | — | US | disclosed |
| CN-118307484-A | Organic electroluminescent compound and organic electroluminescent device comprising the same | 杜邦特种材料韩国有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115108928-B | Nitrogen mustard-tetralone derivative, preparation method and application thereof | 广东海洋大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-110431215-B | Organic electroluminescent compound and organic electroluminescent device comprising the same | 罗门哈斯电子材料韩国有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4051248-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, NEUROLEPTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4051233-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3985731-A | MICROBIOCIDES, MOTOR ACTIVITY INDUCERS, CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637414-B2 | Arylamides and methods of use thereof | CFTR, CLIC1, ABCC1 | MAOA 2504/4885MAOB 2294/4885CYP2A6 98/4885 |
| US-20260055083-A1 | APOL1 INHIBITORS AND METHODS OF USE | APOL1, LDLR, APOB | MAOA 308/4885MAOB 267/4885CYP2A6 1452/4885 |
| US-20240101553-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | MAOA 4876/4885MAOB 4857/4885CYP2A6 3834/4885 |
| US-12630498-B2 | Arylamides and methods of use thereof | CFTR, CLIC1, CLCN2 | MAOA 2651/4885MAOB 2344/4885CYP2A6 93/4885 |
| US-20240270758-A1 | PYRIDINO-OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | KRAS, NRAS, BRAF | MAOA 4400/4885MAOB 3781/4885CYP2A6 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.