Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17983446 | 0.81 | ENPP3 (0.36) | — | |
| SCHEMBL1304283 | 0.79 | PTGS2 (0.41) | DYRK1BPTGS2HDAC6PTGS1CDK2 | |
| SCHEMBL7488038 | 0.78 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8250696 | 0.77 | METAP2 (0.44) | — | |
| SCHEMBL8017036 | 0.76 | MAPT (0.51) | — | |
| SCHEMBL17066733 | 0.76 | ENPP3 (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL28836149 | 0.76 | KMT2A (0.43) | — | |
| SCHEMBL7493475 | 0.75 | PTGS2 (0.45) | DYRK1BPTGS2HDAC6PTGS1 | |
| SCHEMBL3291212 | 0.74 | PTGS2 (0.40) | DYRK1BPTGS2PTGS1 | |
| SCHEMBL24484639 | 0.74 | RAB9A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229839-A1 | Factor XIa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229839-A1 | Factor XIa Inhibitors | F11, SERPINC1, TFPI | DYRK1B 1055/4885PTGS2 1066/4885HDAC6 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.