Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002757 | 0.83 | POLB (0.43) | ALDH1A1POLBL3MBTL1MAPTGRIN1 | |
| SCHEMBL18002212 | 0.83 | L3MBTL1 (0.43) | ALDH1A1POLBL3MBTL1RORCMAPT | |
| SCHEMBL18002394 | 0.82 | CHRNB2 (0.50) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL18002510 | 0.81 | RXRA (0.47) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL18002174 | 0.81 | DRD1 (0.57) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL26683072 | 0.80 | RXRA (0.45) | RXRARXRBALDH1A1MAPTGAA | |
| SCHEMBL21945038 | 0.80 | RXRA (0.50) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL18002087 | 0.78 | PTPN5 (0.46) | ALDH1A1POLBL3MBTL1MAPTMAPK1 | |
| SCHEMBL18002582 | 0.78 | MAPK1 (0.45) | RXRARXRBRXRGALDH1A1POLB | |
| SCHEMBL16398658 | 0.76 | KIF11 (0.41) | RXRARXRBRXRGALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | RXRA 3077/4885RXRB 2771/4885RXRG 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.