Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.46 |
| ▸ | RAB9A | P51151 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 9/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 9/20 | 0.46 |
| ▸ | RELA | Q04206 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.44 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12828975 | 0.83 | DHODH (0.49) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL2315640 | 0.83 | ALDH1A3 (0.62) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL12828980 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL7501277 | 0.80 | ALDH1A1 (0.72) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL2317584 | 0.77 | LMNA (0.33) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL5073469 | 0.77 | DHODH (0.59) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL5249732 | 0.74 | DHODH (0.46) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL12828981 | 0.72 | PARP1 (0.49) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL18003556 | 0.72 | DHODH (0.52) | NPC1RAB9AALDH1A1NFKB1NFKB2 | |
| SCHEMBL22614971 | 0.72 | RAB9A (0.69) | NPC1RAB9AALDH1A1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | NPC1 1062/4885RAB9A 4775/4885ALDH1A1 1611/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | NPC1 1062/4885RAB9A 4775/4885ALDH1A1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.