SCHEMBL1801049

SCHEMBL1801049

CC(C)(C)c1cccc([C]=O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.47
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
ACHE P22303 3/20 0.43
KIF11 P52732 1/20 0.41
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 1/20 0.38
PLA2G1B P04054 1/20 0.38
NFKB1 P19838 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8699521 0.83 CYP1A2 (0.37) HDAC8HDAC4HDAC2KIF11PTPN1
SCHEMBL2517046 0.80 JAK2 (0.38) KIF11PTPN1CYP2C9
SCHEMBL8960313 0.80 HDAC8 (0.44) HDAC8HDAC4HDAC2ACHEKIF11
SCHEMBL16952408 0.78 HDAC8 (0.42) HDAC8HDAC4HDAC2ACHEKIF11
SCHEMBL9204669 0.78 TSHR (0.42) PTPN1CYP3A4
SCHEMBL179266 0.78 KIF11 (0.50) HDAC8HDAC4HDAC2ACHEKIF11
SCHEMBL936277 0.78 PTPN1 (0.51) HDAC8HDAC4HDAC2ACHEKIF11
SCHEMBL97979 0.78 CES2 (0.48) ALDH1A1RAB9APTPN1
SCHEMBL4057658 0.77 GABRA1 (0.40) HDAC8HDAC4HDAC2KIF11RXRA
SCHEMBL1535607 0.77 GABRA1 (0.46) HDAC8HDAC4HDAC2KIF11RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 US disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
CN-104902749-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-103665502-B Composition for conductive rubber roll and conductive rubber roll YAMAUCHI CORP 2015-03-04 CN disclosed
EP-2796455-A1 METHOD FOR PRODUCING SULFONATE Sumitomo Chemical Co., Ltd (JP) 2014-10-29 EP disclosed
EP-1889826-B1 METHOD FOR PRODUCING A HEXAHYDROFUROFURANOL DERIVATIVE SUMITOMO CHEMICAL CO (JP) 2011-10-26 EP disclosed
US-7951977-B2 Process for producing hexahydrofurofuranol derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-31 US disclosed
US-20090176999-A1 Process for producing hexahydrofurofuranol derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-09 US disclosed
EP-1889826-A1 METHOD FOR PRODUCING HEXAHYDROFUROFURANOL DERIVATIVE Sumitomo Chemical Company, Limited (JP) 2008-02-20 EP disclosed
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed
US-5856334-A ANTAGONIST FOR EOSINOPHILS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1999-01-05 US disclosed
EP-0773219-A1 IMIDAZOQUINOLINE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B HDAC8 1881/4885HDAC4 878/4885HDAC2 546/4885
US-20090176999-A1 Process for producing hexahydrofurofuranol derivative DHFR, DHPS, CYP4B1 HDAC8 2968/4885HDAC4 1698/4885HDAC2 1502/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 HDAC8 3536/4885HDAC4 1696/4885HDAC2 1115/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 HDAC8 1140/4885HDAC4 931/4885HDAC2 470/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 HDAC8 2587/4885HDAC4 1826/4885HDAC2 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.